摘要
目的探讨儿童抗感染药物药品不良反应(ADR)的特点,指导临床合理用药。方法对医院2006年至2009年收集的777例抗感染药物ADR报告,建立数据库并进行统计分析。结果 10岁以下儿童发生不良反应较多,致ADR药物以β-内酰胺类较多,临床表现以皮肤损害为主。结论应注意儿童ADR相关因素,重视合理用药,以防止ADR的发生。
Objective To investigate the general patterns and characteristics of children adverse drug reactions （ADR） of anti-infective agents for guiding rational drug use in clinic. Methods Seven hundred and seventy-seven cases of children ADR reports of anti- infective agents collected from our hospital during 2006- 2009 were put into the data base and analyzed. Results Most cases of ADR were teenagers less than 10 years, and the most cases of ADR were caused by β- lactam antibiotics. The clinical manifestations of ADR were mainly skin lesions. Conclusion Most attention should be paid to children ADR related factors and much importance should be attached to rational drug use for preventing the occurrence of children ADR.
出处
《中国药业》
CAS
2012年第17期57-58,共2页
China Pharmaceuticals
