摘要
目的探讨早期肠内外营养对早产儿宫外生长发育的影响,为早产儿制定更为合理的营养支持策略提供指导。方法 2005年12月—2007年1月收治的早产儿87例为对照组,采用保守的营养支持;2009年1月—2011年12月收治的早产儿89例为观察组,严格遵从尽量早开奶(24 h内)、微量喂养、提倡母乳喂养、提供非营养性吸吮、必要时尽早开始积极的肠外营养并在肠内营养耐受后逐渐撤销肠外营养的原则。观察两组早产儿生理性体质量下降持续时间、生后体质量下降幅度、恢复体质量所需时间、达推荐者摄入量(RDIs)所需时间、达足量喂养所需时间、体质量增长速度及平均住院时间。结果观察组和对照组早产儿生理性体质量下降持续时间、生后体质量下降幅度、恢复体质量所需时间、达RDIs所需时间、达足量喂养所需时间、平均住院时间比较,差异均有统计学意义(P<0.05);两组体质量增长速度比较,差异无统计学意义(P>0.05)。观察组和对照组早产儿中极低出生体质量儿生理性体质量下降持续时间、生后体质量下降幅度、恢复体质量所需时间、达RDIs所需时间、达足量喂养所需时间、平均住院时间比较,差异均有统计学意义(P<0.05);两组体质量增长速度比较,差异无统计学意义(P>0.05)。结论尽早开始积极规范的肠内外营养支持对早产儿的生长发育是有利的。
Objective To investigate the effect of early enteral and parenteral nutrition on extranterine growth of pre- mature infants in order to provide guidance for establishing more reasonable nutrition support strategy for premature in- fants. Methods 87 premature infants admitted from December 2005 to January 2007 were involved as control group and were giv- en conservative nutrition support. 89 premature infants admitted from January 2009 to December 2011 were involved as observation group, which strictly followed principles including feeding milk as early as possible （within 24 h）, minimal feeding, breast feeding, giving non -nutritive sucking and early starting of parenteral nutrition and gradual removal of parenteral nutrition after having tolerance of enteral nutrition. The duration of physiological body weight decreasing, decreasing margin of body weight after birth, time for recovering body weight, time to reach RDIs, time to reach sufficient feeding, speed of body weight gain and av- erage hospitalization time of the two groups were observed. Results The duration of physiological body weight decreasing, de- creasing margin of body weight after birth, time for recovering body weight, time to reach RDIs, time to reach sufficient feeding and average hospitalization time of the control group and observation group showed statistically significant differences （ P 〈 0. 05 ）. Speed of body weight gain of the two groups showed no statistically significant difference （ P 〉 0. 05 ） . The duration of physiologi- cal body weight decreasing, decreasing margin of body weight after birth, time for recovering body weight, time to reach RDIs, time to reach sufficient feeding and average hospitalization time of the VLBWI in control group and observation group showed sta- tistically significant differences （ P 〈 0.05 ） . Speed of body weight gain of the VLBWI in the two groups showed no statistically significant difference （ P 〉 0. 05 ） . Conclusion Early beginning of positive and standard enteral and parenteral nutrition support is conducive to the growth of premature infants.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第24期2773-2775,共3页
Chinese General Practice
关键词
肠道营养
胃肠外营养
婴儿
早产
Enteral nutrition
Parenteral nutrition
Infant, premature
