摘要
目的:评估单孔腹腔镜手术对异位妊娠、不孕症患者机体应激及代谢的影响。方法:选择2012年1月至2012年6月56例异位妊娠、不孕症患者,以非随机方式分为单孔腹腔镜组(n=26)与传统腹腔镜组(n=30)。分别检测术前24 h、术后24 h、术后72 h血清中皮质醇、甲状腺激素及肝酶水平。结果:两组患者术后皮质醇均升高,传统组术后24 h皮质醇变化较显著,两组均于术后72 h恢复至术前水平。单孔组手术前后甲状腺相关激素水平较传统组轻微且恢复迅速,传统组波动较大。两组患者肝酶影响不明显。单孔组手术时间长于传统组。结论:单孔腹腔镜手术较传统腹腔镜手术对机体应激及代谢影响小,手术更微创,其安全性及有效性尚待大样本及长时间的对比研究。
Objective：To evaluate the effect of transumbilical single-port laparoscopic operation for the treatment of ectopic pregnancy and infertility on patients＇stress metabolism. Methods：Fifty-six cases of ectopic pregnancy and infertility patients adopted from Jan. 2012 to Jun. 2012 were divided into single-port group （n = 26） and traditional laparoscopie group（ n = 30）. Serum cortisol, FT3, FT4, TSH, ALT, AST were measured at 24 h preoperatively,24 and 72 h postoperatively. Remdts ： The cortisol level of both groups arised after operation and recovered to normal level 72 h postoperatively, while the cortisol level of traditional laparoscopic group measured at 24 h postoperatively was higher than that of the single-port group. FT3, FT4 and TSH levels of the single-port group changed less and recovered faster than those of the traditional laparoscopic group. There was no obvious changes in ALT and AST levels of both groups. The operation duration of the traditional group was longer than that of the single-port group. Conclusions ： Compared with the traditional laparoscopy, single-port laparoscopic surgery has less effect on patients＇metabolic and stress response, and brings less trauma. The efficacy and safety of the approach need to be confirmed by large sample and long time comparative study.
出处
《腹腔镜外科杂志》
2012年第9期664-666,共3页
Journal of Laparoscopic Surgery
基金
深圳市医学科技计划项目(编号:201103302)
关键词
异位妊娠
不孕
女性
腹腔镜检查
单孔
应激
代谢
Ectopic pregnancy
Infertility, female
Laparoscopy
Single-port
Stress
Metabolic
