摘要
阻塞性睡眠呼吸暂停低通气综合征(OSAHS)由睡眠期间上气道反复阻塞导致,以频繁低通气、呼吸暂停、低氧血症和睡眠觉醒为基本病理生理改变,主要表现为夜间打鼾,白天嗜睡,感知功能受损。本病如不及时治疗,长期发展可引起高血压、脑卒中、冠心病、心律失常、糖耐量异常、认知功能障碍等。本文总结近年来相关的文献报道,探讨OSAHS与高血压之间的关系,明确了OSAHS是高血压发生的独立危险因素,而持续正压通气(CPAP)治疗可以显著降低高血压引起的心血管风险。
] Obstructive sleep apnea hypopnea syndrome （OSAHS） is caused by repetitive closing of upper airway with frequent hypopnea, apnea, hypoxemia and awakening as basic pathophysiologic changes. It is mainly characterized by snoring at night, somnolence in the daytime and impaired perceptional function. If not treated in time, OSAHS can cause hypertension, stroke, coronary heart disease, arrhythmia, impaired glucose tolerance and cognitive impairment in the long run. This article summarizes the literatures on OSAHS in recent years, discusses the relationship between OSAHS and hypertension and proves that OSAHS is the independent risk factor for hypertension and continuous positive airway pressure （CPAP） can significantly reduce the risk of cardiovascular diseases caused by hypertension.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第27期3095-3098,共4页
Chinese General Practice
