摘要
【目的】探讨眼部缺血综合征的临床特征以及高血压对视力和眼底病变的影响。【方法】对124例眼部缺血综合征患者的病例资料进行回顾性分析。【结果】124例患者平均年龄63.64(S=12.13)岁,男女比例1.8∶1;96.77%的患者有颈动脉狭窄,主要的全身合并症是高血压,糖尿病和心脑血管疾病;主要眼部症状为视力下降和一过性黑矇,眼前节主要发生虹膜新生血管生成,视网膜主要表现为动脉狭窄和静脉扩张、点片状出血;眼底荧光血管造影主要表现为臂-视网膜循环时间和视网膜动-静脉循环时间延长、微血管囊样扩张和毛细血管无灌注区;合并高血压的患者的视力障碍与没有高血压的患者相比差异有统计学意义(P<0.01)。【结论】眼部缺血综合征是一种主要发生于老年人的严重的慢性缺血性眼部症候群,男性多于女性,主要由颈动脉狭窄引起,临床表现复杂多样,常常需要神经科和心内科等医师联合诊治,高血压可以加重患者的眼部病变,眼底镜和荧光血管造影检查是早期确诊该病的关键手段。
[Objective] The project investigated clinical features of ocular ischemic syndrome （OIS） and the influence of hypertension on vision and fundus lesion. [Method] Retrospective analysis was performed on 124 patients of OIS. [Results] Mean age of all patients was 63.64 （S = 12.13）, with a ratio of 1.8：1 between male and female. Among all patients, 96.＇77% were detected carotid artery stenosis, mainly accompanied by hypertension, diabetes and cardiovascular and cerebrovascular disease. They presented with reduced visual acuity and amaurosis fugax, along with iris neovascularization at anterior segment and arteriostenosis, phlebectasia, dot and blot hemorrhage at retina by ophthalmoscope examination. Fundus fluorescein angiography （FFA） exhibited prolongation of arm-retina time and arteriovenous circulation time, microaneurysms and capillary non-perfusion region. And visual disturbance between normotensive and hypertensive patients showed significant difference （P 〈 0.01 ）. [Conclusion] OIS, characterized as complicated clinical mamfestations and deteriorated by hypertension, is mainly induced by carotid stenosis, commonly seen among aged population. Ophthalmoscope examination and FFA afford key methods for its early diagnosis with co-diagnosis and co-treatment from neurologist and cardiologist.
出处
《中山大学学报（医学科学版）》
CAS
CSCD
北大核心
2012年第4期536-540,共5页
Journal of Sun Yat-Sen University:Medical Sciences
关键词
眼部缺血综合征
颈动脉狭窄
高血压
眼底荧光血管造影
眼底镜检查
ocular ischemic syndrome
carotid artery stenosis
hypertension
fundus fluorescein angiography
ophthalmoscopeexamination
