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抗菌肽的研究及进展 被引量:6

Research Progress in Antimicrobial Peptides
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摘要 抗菌肽是一种广泛存在于各类生物体内具有生物活性的小分子多肽,它是构成机体天然免疫系统的重要组成部分。各种研究结果表示,抗菌肽不但有抗菌抑菌功能,同时还有抗病毒、抗肿瘤的功效。现对抗菌肽在抑菌活性、作用机制以及人工制备方法等进行总结,并简要介绍目前抗菌肽在各个领域的应用情况及发展进程。 Antimicrobial peptides, a kind of small peptides with biological activity, widely existing in va- rious organisms. Antimicrobial peptides are an important component of the innate immune system of organ- isms. Many findings suggest that antimicrobial peptides not only have the capabilities of antibacterial and in- hibition, but also anti-virus and anti-tumor. Here is to summarize the activity, mechanism of action and meth- od of artificial preparation of antimicrobial peptides, and briefly introduce its application and development in each field.
出处 《医学综述》 2012年第19期3172-3175,共4页 Medical Recapitulate
基金 武汉农业科学研究项目(201120722216-2)
关键词 抗菌肽 作用机制 应用 发展 Antimicrobial peptides Mechanism Application Development
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