摘要
目的分析中国登革热患者发病至确诊间隔时间（间隔时间）及其影响因素。方法对传染病监测信息系统中的数据进行描述性分析，采用非参数检验和logistic回归分析间隔时间的影响因素。结果发病至确诊间隔时间呈正偏态分布，中位数为6d，四分位数间距为4d，有57．8％的患者间隔时间〉5d。影响因素分析显示输入病例、年长者、非流行季节及福建、云南和浙江省的病例间隔时间较长。输入病例间隔时间中位数为6d，比本地病例多1d；非流行月份比流行月份间隔时间中位数多1d；福建、云南省间隔时间中位数为7d，比广东省多1d；20岁以下患者间隔时间中位数为5d，较20岁以上人群少1天。结论大部分登革热患者在病毒血症期不能被确诊，需要增强监测系统的敏感性，尤其是在登革热的流行地区和非流行季节。
Objective To study the time between the onset and diagnosis of Dengue fever and its influencing factors in China. Methods Data were obtained from the Infectious Disease Surveillance System （IDSS）. Descriptive analysis was performed for the time interval while nonparametric tests and logistic regression analysis were used to study the related influencing factors. Results Time interval appeared positively skewed with distribution at median of 6 days, quartile range as 4 days, while 57.8% of them were longer than five days. Data showed that patients with longer intervals among the imported cases, being elderly, cases in non-endemic season and provinces as Fujian, Yunnan and Zhejiang appeared to have had greater influences on the disease. Median of those imported cases was six days, one day longer than locally generated cases, while median of the non- epidemic month was one day more than that of the epidemic month. In Fujian and Yunnan provinces, the medians were 7 days, one day more than that from Guangdong province. The median among young people was 5 days, one day less than that of the patients older than 20 years of age. Conclusion Most Dengue patients did not get diagnosed early enough so it was of urgent need to enhance the sensitivity of the monitoring system, especially in epidemic regions and during non-epidemic season.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2012年第10期1064-1066,共3页
Chinese Journal of Epidemiology
基金
国家自然科学基金（30972563）
卫生行业科研专项（201202006）
山东省国内访问学者项目
关键词
登革热
发病至确诊时间
Dengue fever
Time between onset and diagnosis
