摘要
目的评价4%高渗盐水雾化吸入治疗婴幼儿喘息的疗效及安全性。方法毛细支气管炎、喘息性支气管炎和支气管肺炎伴有喘息症状的住院患儿90例,按入院时间的先后随机分成治疗组46例,对照组44例。在常规治疗的基础上治疗组给予4%高渗盐水雾化吸入,其他与对照组相同。结果 2组在治疗后第3、4、5、7 d的临床症状评分相比,差异有统计学意义(P﹤0.05),平均住院天数相比,差异也有统计学意义(P﹤0.05),治疗组住院天数较对照组减少15.6%,治疗组与对照组的痰诱导成功率分别为60.9%和22.7%,两组比较,差异有显著统计学意义。结论 4%高渗盐水雾化吸入治疗婴幼儿喘息性疾病有利于痰液排出,改善呼吸道症状,缩短住院时间。
Objective To evaluate the efficacy and safety of inhaled 4% hypertonic saline solution with salbutamol,budesonide for infant wheezing.Methods A total of 90 infants with bronchiolitis,asthmatic bronchitis,bronchopneumonia with wheezing were randomly divided into two groups by the sequence of admittance to hospital：treatment group（n=46） and control group（n=44）.Salbutamol and budesonide mixtured with 2.5 ml 4% hypertonic saline solution were inhaled for treatment group.The two groups received inhalation for the base of routine therapy.Inhalation was repeated for three times every day until wheezing relieved.Results The clinical score of two groups on the third,fourth,fifth and seventh day had significant difference（P﹤0.05）.The score of wheezing on the third,fourth,fifth,sixth and seventh day in treatment group was significantly lower than that in control group（P﹤0.05）.The mean length of hospital stay in the treatment group and control group showed different（P﹤0.05）.The mean length of hospitalization in the treatment group had a relevant 15.6% reduction as compared with control group.The success rate of sputum induction in treatment group and control group was 60.9% and 22.7%,respectively.There was significant difference between the two groups（P0.01）.Conclusion Nebulized 4% hypertonic saline with salbutamol,budesonide in infant wheezing can decrease length of hospitalization,improve respiratory symptoms of wheezing,cough and asthmatic noise,induce sputum.
出处
《河南职工医学院学报》
2012年第5期595-598,共4页
Journal of Henan Medical College For Staff and Workers
关键词
婴幼儿
喘息
高渗盐水
生理盐水
infant
wheezing
hypertonic saline
normal saline
