摘要
目的调查柳州市妇幼保健院儿童感染鲍氏不动杆菌的耐药性,以指导临床治疗。方法采用美国的MicroScan WalkAway 40型微生物分析仪对细菌进行鉴定并做药敏试验,对近两年分离出的鲍氏不动杆菌的耐药性进行分析。结果 3114株革兰阴性杆菌中,鲍氏不动杆菌分离出139株,占4.5%;标本的主要来源是痰液;在常规监测的12种抗菌药物中,总体耐药性低,其中对亚胺培南的耐药性最低,为1.4%,其次为左氧氟沙星3.4%,环丙沙星2.9%,对三代、四代头孢类药物的耐药率均<10.0%。结论呼吸道标本是鲍氏不动杆菌的主要来源,在治疗儿童鲍氏不动杆菌感染中,亚胺培南、第三代、四代头孢类药物是较好的选择。
OBJECTIVE To investigate the antimicrobial resistance of Acinetobacter baumannii causing infection in children in Liuzhou Maternal and Children Hospital so as to guide the clinical treatment.METHODS The bacteria were identified and detected by MicroScan WalkAway 40,the drug susceptibility testing was performed.Retrospective analysis of the drug resistance of A.baumannii strains isolated during the past two years was carried out.RESULTS Of 3114 strains of gram-negative bacilli,there were 139 strains of A.baumannii isolated with the isolation rate of 4.5%;the isolates were mainly from sputum;the result of drug susceptibility testing showed that the drug resistance of A.baumannii to 12 antibiotics was generally low,the drug resistance rate to imipenem was the lowest（1.4%）,followed by levoflaxacin（2.9%） and ciprofloxacin（3.6%）,the drug resistance rates to the third and fourth generation of cephalosporins were less than 10.0%.CONCLUSION A.baumannii isolates are mainly from respiratory tract;imipenem and the third and fourth generation of cephalosporins are preferred antibiotics for the treatment of A.baumannii infections in children.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第19期4360-4361,4384,共3页
Chinese Journal of Nosocomiology
关键词
鲍氏不动杆菌
耐药性
抗菌药物
儿童
Acinetobacter baumannii
Drug resistance
Antibacterial agents
Children
