摘要
目的:观察肾康注射液治疗糖尿病肾病的效果。方法:治疗组34例,采取肾康注射液与基础治疗联合治疗,并选择同期采取基础治疗但未用肾康注射液的52例患者作为对照组,基础治疗为胰岛素控制血糖,血管紧张素转化酶抑制剂(ACEI)及血管紧张素Ⅱ受体拮抗剂(ARB)类降压药物控制血压,辅以控制饮食、对症治疗。肾康注射液应用方法为100ml,加入5%葡萄糖液300ml,静脉滴注,1次/d,两组疗程为28d。结果:两组在尿蛋白定量、肌酐、尿素氮、空腹血糖、胆固醇及甘油三酯等6个指标方面均有明显的疗效(P<0.0001);组间比较,除空腹血糖外(P=0.7748),治疗组在尿蛋白定量(P<0.0001)、肌酐(P<0.0001)、尿素氮(P=0.0383)、胆固醇(P=0.0369)及甘油三酯(P=0.0064)5个指标改善方面均优于对照组。结论:肾康注射液具有显著地改善糖尿病肾病肾功能,降低血脂的作用。
Objective：To evaluate the efficacy of Shenkang injection in treatment of diabetic nephropathy.Method：The treatment group included 34 patients who were taken combination therapy of Shenkang injection and basic treatment.The control group included 52 patients at the same period who were taken a basic treatment without Shenkang injection.The basic treatment was controlling blood sugar with insulin,controlling blood pressure with ACEI and ARB,controlling diet and symptomatic treatment.The application methods of Shenkang injection was that,adding 5% glucose solution 300 ml in Shenkang injection 100 ml,intravenous infusion,1 time per day,the treatment lasted for 28 days.Result：The two groups had both efficacy in urinary protein excretion,creatinine,urea nitrogen,fasting blood glucose,cholesterol and triglycerides.The efficacy of the treatment group was better than that of the control group in urinary protein excretion,creatinine,urea nitrogen,cholesterol and triglycerides.Conclusion：Shenkang injection can significant improve renal function and reduce blood lipids of diabetic nephropathy.
出处
《中国医学创新》
CAS
2012年第30期9-10,共2页
Medical Innovation of China
关键词
肾康注射液
糖尿病肾病
Shenkang injection
Diabetic nephropathy
