摘要
目的观察丹红联合腺苷钴胺对糖尿病周围神经病变(diabetic peripheral neuropathy,DPN)合并ST-T波改变患者疗效。方法选取2011年9月～2012年9月我院收治的DPN合并ST-T波改变患者100例作为研究对象。将患者随机分为两组,每组各50例。两组患者治疗前后均进行糖尿病健康教育及降糖治疗,对照组给予腺苷钴胺针500μg/d;治疗组在此基础上给予丹红注射液30 mL/d。治疗四周后对疗效进行评价。结果治疗组50例中显效35(70.0%)例,好转9(18.0%)例,无效6(12.0%)例,总有效率为88.0%,有效率明显高于对照组,差异具有统计学意义(χ2=4.00,P<0.05);两组患者右正中运动神经、右正中感觉神经、左腓总运动神经和腓总感觉神经神经传导速度均显著提升(P<0.05);治疗组患者右正中运动神经、右正中感觉神经、左腓总运动神经和腓总感觉神经传导速度显著高于对照组(P<0.05)。结论丹红注射液联合腺苷钴胺可有效改善DPN合并ST-T波改变患者周围神经损伤及心功能。
Objective To study the effects of Danhong Injection combined with Adenosine cobalamin on diabetic peripheral neuropathy （DPN） patients with ST-T changes. Methods From Sep 2011 to Sep 2012, 100 DPN patients with ST-T changes were selected from our hospital. Patients randomly divided into treatment group （50 cases） and the control group （50 cases）. All of the patients received dealth education on diabetes melfitus and diabetes treatment.Control group treated with 500 tzg/d Adenosine cobalamin; on this basis, treatment group was given 30 mL/d danhong injection. Effects were evaluated after treatment for four weeks. Results Fifty cases in the treatment group, 35 cases （70.0%） had an effects, 9 cases （18.0%） improved, and 6 cases （12.0%） invalid, total effective rate was 88.0%, effective rate was significantly higher in the treat- ment group than in the control group, the difference was statistically significant （X2=4.00, P 〈 0.05）; Two groups of patients with median motor neurons, sensory neurons in the middle-right, left-right common Peroneal motor nerve and common Peroneal are significantly improved sensory nerve conduction velocity （P 〈 0.05）; Treatment in patients with median motor neurons, sensory neurons in the middle-right, left-right common Peroneal common Peroneal sensory nerve conduction ve- locity of motor neurons and substantially higher than the control group （P 〈 0.05）. Conclusion Danhong Injection combined with Adenosine cobalamin can effectively improve peripheral nerve injury and cardiac function in DPN patients with ST-T changes.
出处
《中国现代医生》
2012年第30期74-75,77,共3页
China Modern Doctor
基金
浙江省乐清市科技项目(2011Y010)
关键词
DPN
ST—T波改变
丹红
腺苷钴胺
Diabetic peripheral neuropathy
ST-T changes
Danhong Injection
Adenosine cobalamin
