摘要
目的:探讨纳米碳混悬液注射对乳腺癌前哨淋巴结示踪的效果。方法:对36例乳腺癌患者,术前30 min于乳晕周围分4点皮下均匀注射纳米碳混悬液,找到腋窝黑染淋巴结确定为前哨淋巴结,然后行乳腺癌改良根治或保乳手术。结果:全组成功检查前哨淋巴结34例,检出率为94.4%(34/36);准确率为91.6%(33/36),灵敏度为93.3%(14/15);假阴性率6.6%(1/15),假阳性率为0。结论:纳米碳混悬液作为示踪剂能准确反映腋窝淋巴结转移状态,对指导乳腺癌根治性切除术范围具有临床应用价值。
Objective： To investigate the effect of carbon nanoparticle suspension injection on sentinel lymph node （SLN） mapping of breast cancer. Methods： Thirty-six patients with breast cancer were subcutaneously injected with carbon nanoparticle suspension into four equal depots around the areola 30 min before surgery The black stained axillary lymph nodes were found and labeled as SLNs, and then modified radical mastectomy or breast-conserving surgery was performed. Results： SLNs in 34 cases of the entire group were successfully detected and the detection rate was 94.4%（34/36）. The accuracy rate and sensitivity was 91.6% （33/36） and 93.3% （14/15）, respectively. The false-negative rate was 6.6% （1/15）, and there were no false-positive results. Conclusion： Using carbon nanoparticle suspension as a tracer can correctly reveal the status of axillary lymph nodes, and it may provide appropriate guidance on the scope of radical resection for breast cancer.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2012年第11期1346-1349,共4页
China Journal of General Surgery
关键词
乳腺肿瘤
前哨淋巴结活组织检查
纳米碳
Breast Neoplasms
Sentinel Lymph Node Biopsy
Carbon Nanoparticle
