摘要
目的探讨精氨酸协同瑞甘(门冬氨酸鸟氨酸)治疗肝性脑病的临床疗效。方法将52例肝性脑病患者随机分为实验组26例和对照组26例。对照组给予常规治疗,实验组在常规治疗的基础上加用精氨酸和门冬氨酸鸟氨酸,连用7d。观察两组患者治疗前后血氨(NH3)和肝功能指标、意识变化,并对总有效率进行比较。结果实验组治疗后血氨水平、TBIL、ALT下降幅度高于对照组,差异有统计学意义(p<0.05);实验组清醒时间短于对照组,差异有统计学意义(p<0.05);实验组总有效率为88.4%,高于对照组的65.4%,差异有统计学意义(p<0.05)。结论精氨酸联合门冬氨酸鸟氨酸治疗肝性脑病疗效确切。
Objective To probe into the clinical therapeutic effect of arginine in combination with ornithine aspartate on hepatic encephalopathy.Method 52 patients with hepatic encephalopathy were divided into experimental group with 26 cases and control group with 26 cases randomly.The control group had routine treatment while the experimental group was treated with arginine in combination with ornithine aspartate on the basis of routine treatment for 7 days.The blood ammonia(NH3),liver function index and conscious modification of patients in the two groups before and after the treatment were observed and the total effective rate was compared.Results The decrease of NH3 level,TBIL,ALT was more prominent in the experimental group than in the control group after the treatment,and the differences were statistically significant(p<0.05);the recovery time of the experimental group was shorter than that of the control group,and the differences were statistically significant(p<0.05);the total effective rate in the experimental group was 88.4%,which was higher than that in the control group of 65.4%,and the differences were statistically significant(p<0.05).Conclusion Arginine in combination with ornithine aspartate has definite therapeutic effect in treating the hepatic encephalopathy.
出处
《保健医学研究与实践》
2012年第2期45-47,共3页
Health Medicine Research and Practice
关键词
精氨酸
门冬氨酸鸟氨酸
肝性脑病
Arginine
Ornithine aspartate
Hepatic encephalopathy
