摘要
建立了同时测定调味品中糠醛、5-甲基糠醛和5-羟甲基糠醛的气相色谱-串联质谱法(GC-MS/MS)。对样品的前处理方法及GC-MS/MS分析条件进行优化,样品经乙酸乙酯萃取,GC-MS/MS多反应监测模式(MRM)进行测定。3种糠醛类物质在0.001～20 mg/L范围内均呈良好的线性关系,相关系数为0.999 0～0.999 5;检出限(S/N=3)均为0.005 mg/kg,加标回收率为86%～95%。该法简便、快速、溶剂用量少,可消除调味品中复杂基质的干扰,结果准确可靠、灵敏度高,适用于调味品中3种糠醛类物质的同时测定。
A method for the determination of furfural, 5-methylfurfural and 5-hydroxymethylfurfural in eondimen by gas chromatographytandem mass spectrometry （GC -MS/MS） was developed. In this paper, the conditions for sample pretreatment and GC -MS/MS were investigated and optimized. The samples were extracted with ethyl acetate. The detection was carried out by GC -MS/MS under the multiple-reaction monitoring（MRM） mode. Good linear relationships were obtained in the concentration range of 0. 001 - 20 mg/L of three analytes, with correlation coefficients of 0. 999 0 - 0. 999 5. The limits of detections （ S/N = 3 ） of three compounds were all 0. 005 mg/kg, and the recoveries ranged from 86% to 95% . This method showed the advantages of simplicity, rapidness and low solvent consumption, and the complex matrix disturbance in condimen samples could be eliminated when MRM mode was adopted.
出处
《分析测试学报》
CAS
CSCD
北大核心
2012年第11期1345-1351,共7页
Journal of Instrumental Analysis
基金
广东省科技计划项目(2010A010500004)
广东省地方标准(调味品中糠醛的测定方法--气相色谱-质谱法)
