摘要
目的:探讨思密达联合干扰素治疗小儿轮状病毒性肠炎的临床效果。方法:选择近期于笔者所在医院儿科就诊的80例小儿轮状病毒性肠炎患儿作为观察组,收集之前于笔者所在医院治疗的50例小儿轮状病毒性肠炎患儿作为对照组,比较两组治疗后止吐时间、退热时间、止泻时间、脱水纠正时间及电解质紊乱纠正时间等指标及预后情况。结果:观察组患儿退热时间(1.9±0.7)d,止泻时间(3.1±0.7)d,脱水纠正时间(2.0±0.6)d、电解质紊乱纠正时间(2.6±1.0)d,均优于对照组(P<0.05);其显效率81.3%、总有效率95.0%,也显著优于对照组(P<0.05)。结论:干扰素肌注联合思密达口服治疗小儿轮状病毒性肠炎具有较好的临床效果,缩短了疗程,缓解了患儿病痛,具有一定的临床应用价值。
Objective ： To investigate the clinical effect of smecta in combination with interferon therapy in children with rotavirus enteritis. Methods ： Recent hospital pediatric clinic 80 cases of children with rotavirus enteritis as the observation group were includedl, and collected clinical data of 50 cases of children with rotavirus enteritis in children in our hospital as a control group, to compare the two groups of treatment after antiemetic time, fever clearance time, the antidiarrheal time, dehydration corrected time and intravenous fluids to correct electrolyte imbalance time and prognosis. Results ： Interferon in combination with smecta observation children had a fever clearance time of（1.9 ＋ 0.7）d, the antidiarrheal time（3.1 ＋ 0.7）d, dehydration corrected time （2.0 4- 0.6）d, electrolyte imbalance corrected time of（2.6 ~ 1.0）d, which were significantly better than control group （＊~〈0.05） ; The remarkable efficiency was 81.3% and the total efficiency was 95.0%, which was significantly better than the control group （P〈0.05）.Conclusion ： Intramuscular injection interferon combining with smectite oral treatment of mild to moderate rotavirus enteritis in children with good clinical results has its advantages such as shortening the course of treatment, ease the pain of children.
出处
《中外医学研究》
2012年第32期7-9,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
