摘要
目的探讨质子泵抑制剂(PPI)联合生长素治疗非静脉曲张性上消化道大出血的临床疗效。方法选择180例非静脉曲张性上消化道大出血患者,随机分为对照组(90例)与观察组(90例),对照组使用PPI,观察组使用PPI联合生长素,观察两组患者的总有效率、止血时间、输血量以及再出血等情况。结果观察组总有效率(92.2%)明显高于对照组(83.3%)(P<0.01);观察组止血时间[(23.5±3.5)h]、输血量[(4.1±0.5)U]、再出血率(3.3%)明显低于对照组(P<0.01)。结论 PPI联合生长抑素治疗非静脉曲张性上消化道大出血,止血效果更快,临床疗效更佳,再出血发生率更低。
Objective To explore the clinical effect on Proton Pump Inhibitor combined with Somatostatin in the treatment of non-varicose massive upper gastrointestinal hemorrhage.Methods Clinical data of 180 patients with non-varicose massive upper gastrointestinal hemorrhage were divided into control group（90 cases） and observation group（90 cases）.Control group was given PPI,while observation group was given PPI combined with Somatostatin.Effective rate,time for stanching,amount of blood transfusion,and recurrence of hemorrhage in both groups were observed.Results The total effective rate in observation group was 92.2%,which was obviously higher than that of control group（83.3%）（P〈0.01）.Time for stanching,blood transfusion,and hemorrhage recurrence rate in observation group were（23.5 ±3.5）h,（4.1±0.5）U and 3.3% respectively,which were remarkably lower than those of control group（P〈0.01）.Conclusion Non-varicose massive upper gastrointestinal hemorrhage treated by PPI on the combination of somatostatin is with faster blood stanching,lower hemorrhage recur rence rate and better clinical effect.
出处
《中国医药导报》
CAS
2012年第32期156-157,共2页
China Medical Herald
关键词
质子泵抑制剂
生长抑素
非静脉曲张性上消化道大出血
疗效
Proton pump inhibitor
Somatostatin
Non-varicose massive upper gastrointestinal hemorrhage
Effect
