摘要
目的了解广州地区健康人群中的EB病毒感染情况。方法采用ELISA法检测2007年1月至2011年12月本院体检的217935例健康人的EB—VCA—IgA抗体，统计对比男女阳性率、5年问阳性率及各年龄段（≤29岁、30，39岁、40～49岁和≥50岁5个组）阳性率的差异。结果EB—VCA-I酗抗体阳性4667例，总阳性率2．14％。其中男性135985例，阳性率1．87％（2547／135985）；女性81950例，阳性率2．59％（2120／81950），男女阳性率差异有统计学意义（P：0．000）。5年间各年阳性率差异有统计学意义臼z=576．054，P=0．000）。EB—VCA．IgA抗体的阳性率随着年龄的增长而增高，各年龄段差异均有统计学意义（P=0．000）。结论广州地区健康人群中有一定比例的EB病毒感染者，且40岁以上健康人群感染率相对较高。
Objective To determine the Epstein-Ban virus（EBV） infection in healthy population in Guangzhou. Methods A total of 217 935 healthy individuals who received health check-up in The General Hospital of Guangzhou Military Command between January 2007 and December 2011 underwent screening of EB- VCA-IgA antibody via enzyme-linked immunosorbent assay. This was followed by comparison on positive rate of both sexes, within the 5 years and at various age groups （ ~〈 29 years, 30-35 years, 40-49 years and ~ 50 years）. Results Of 217 935 individuals assayed, 4667（2.14%） were positive to EB-VCA-IgA antibody. The positive rate differed significantly（P=O.000） between males（ 1.87%, 2547/135 985） and females （2120/81 950, 2.59%） and varied within the 5 years0（Z=576.054, P=0.000）. The positive rate of EB-VCA-IgA antibody varied among different age groups（P=O.O00）, and increased with the age. Conclusions EB virus infection can be found in a subgroup of healthy population in Guangzhou. A higher incidence of EBV infection is mostly associated with healthy individuals aged 〉40 years.
出处
《中华生物医学工程杂志》
CAS
2012年第5期410-412,共3页
Chinese Journal of Biomedical Engineering
关键词
疱疹病毒4型
人
抗体
病毒
健康人群
酶联免疫吸附测定
Herpesvirus 4, human
Antibodies, viral
Healthy population
Enzyme-linkedimmunosorbent assay
