摘要
目的探讨奥曲肽、垂体后叶素治疗肝硬化上消化道出血的疗效。方法将肝硬化上消化道出血的120例患者,随机分为奥曲肽组和垂体后叶素组,观察2组患者止血和不良反应发生情况。结果奥曲肽组治疗的临床显效率、总有效率明显高于例垂体后叶素组[40.0%(24/60)比21.7%(13/60),75.0%(45/60)比53.3%(32/60)(]P<0.05),奥曲肽组止血时间、不良反应发生率均明显低于垂体后叶素组[(21±11)h比(34±14)h,8.3%(5/60)比38.3%(23/60)(]P<0.01)。结论在肝硬化上消化道出血的治疗中,奥曲肽的疗效高于垂体后叶素,具有一定临床价值。
Objective To investigate the efficacy of octreotide, pituitrin in treatment of upper gastrointestinal hemorrhage in hepatic cirrhosis. Methods Chose 120 patients with upper upper gastrointestinal hemorrhage in hepatic cirrhosis, and divided them into two groups, the octreotide group and pituitrin group. The hemostasis and adverse reactions were observed in two groups. Results Clinically significant efficiency, total efficiency of the octreotide group was significantly higher than the pituitrin group （P〈0.05）, hemostatic time and adverse reaction rates of the octreotide group were significantly lower than the pituitrin group （P〈0.01）. Conclusion In the treatment of upper gastrointestinal hemorrhage in hepatic cirrhosis, the efficacy of the octreotide group is higher than the pituitary group, it has a certain clinical value.
出处
《当代医学》
2013年第1期135-136,共2页
Contemporary Medicine
关键词
奥曲肽
垂体后叶素
肝硬化
上消化道出血
Octreotide
Pituitrin
Hepatic cirrhosis
Upper gastrointestinal hemorrhage
