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食管癌患者三维适形放疗联合同步化疗的临床观察 被引量:1

Clinical Observation of Three-dimensional Conformal Radiotherapy with Concurrent Chemotherapy in Patients with Esophageal Cancer
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摘要 目的观察食管癌患者应用三维适形放疗与TP同步化疗方案进行联合治疗的临床效果。方法对116例食管癌患者临床资料进行回顾性分析,将其分为A、B两组,A组60例(同步放化疗),B组56例(单纯放疗),A、B两组患者均进行三维适形放疗,采取常规分割,每次200cGy,qd,每周5d,其处方剂量为6000~7000cGy。A组化疗第1d静滴紫杉醇135mg/m2,第1~3d静滴顺铂30mg/m2。其化疗均于放疗的第1与第29d实施,为2周期。结果 A组近期有效率达到93.33%,B组仅75.00%,差异显著(P<0.05);A组1、2、3年生存率分别是78.8%、67.2%及49.97%,B组则分别是69.1%、50.13%及37.38%,均不具显著差异(P>0.05);两组主要不良反应为白细胞减少以及放射性食管炎。结论食管癌患者应用三维适形放疗与TP同步化疗方案进行联合治疗,其不良反应呈略增加趋势,但予以对症处理,均能耐受,近期的疗效显著,应予推广。
作者 郭雪娟
出处 《现代诊断与治疗》 CAS 2012年第10期1633-1634,共2页 Modern Diagnosis and Treatment
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  • 1周丹,章淑华,许小江,隋杰.内镜直视下支架置入治疗食管恶性狭窄的应用[J].吉林医药学院学报,2007,28(1):36-37. 被引量:6
  • 2Watkinson AF, Ellul J, Entwisle K, et al. Esophageal carcinoma: Initial results of palliative treatment with covered self-expanding endo prostheses [ J ] . Radiol, 1995, 195(3): 821-827.
  • 3Segalin A, Bonavina L, Carazzone A. Improving results of esophageal stenting: A study on 160 consecutive unselected patients [ J ]. Endoscopy, 1997, 29(8): 701-709.
  • 4Ludwig D, Dehne A, Burmester E. Treatmenl of unresectahl.e carcinoma of the esophagus or the gastroesophageal junction by Mesh stents with or without radio-chemotherapy [ J ] . Int J Oncol, 1998, 13(3): 583-588.
  • 5Wang MQ, Sze DY, Wang Z, et al. Delayed complications after esophageal stent placement for treatment of malignant esophageal obstructions and esophagorespiratory fistulas [ J ] . JVIR, 2001, 12(4): 465-474.
  • 6Song HY, Do YS, Han YM, et al. Covered, expandable esophageal metallic stent tubes :Experiences in 119 patients [ J ] . Radiol, 1994, 193(3): 689-695.
  • 7Siersema PD, Tan TG, Sutorius FF, et al. Massive hemorrhage caused by a perforating Gianturco-Z stent resulting in the an aortoesophageal fistula [ J ] . Endoscopy, 1997, 29 ( 7 ) : 416-420.
  • 8Cooper JS, Guo MD, Herskovie A, et al. Chemoradiotherapy of locally advanced esophageal eancer: long-term follow-up of a prospective randomized trial( RTOG 85-01 ). Radiation Therapy Oneology Group[J]. JAMA, 1999,281 (17) :1623-1627.
  • 9Asakura H, Takashima H, Yokoe K, et al. Hyperfraetionated radiotherapy with concurrent chemotherapy for advanced esophageal cancer[J]. Gall To Kagaku Ryoho, 2005,32(9) :1279-1282.
  • 10Wong R, Malthaner R. Combined chemotherapy and radiotherapy (without surgery) compared with radiotherapy alone in localize carcinom of the esophagus[ J]. Coehrane Database Syst Rev, 2006,25( 1 ) :2092.

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