摘要
目的了解广东省超重肥胖2型糖尿病（T2DM）患者血糖控制现状和相关影响因素。方法2011年8月至2012年3月在广东省内60家二级以上医院门诊就诊或住院的已确诊T2DM且合并超重或肥胖的常住居民进行横断面调查，共纳入调查超重肥胖T2DM患者5241例，通过填写调查问卷和体格检查的方式获取患者临床资料，了解影响血糖控制的因素。以糖化血红蛋白（HbAlC）评价血糖控制水平，以HbAlC〈7．0％为血糖控制达标。结果4768例完成研究，其中男2252例，女2516例。患者年龄59．0（50．0～69．0）岁；发病年龄52．0（44．0—60．0）岁；病程5．0（2．0～11．0）年。体质指数（BMI）为26．33（24．88—28．34）kg／m2；腰围为93．0（88．0～100．0）cm。HbAle为8．1％（6．9％～10．1％），仅26．2％的超重肥胖T2DM患者HbAlc达到控制目标。向心性肥胖、静息心率偏快、合并脂肪肝及糖尿病治疗强度大的患者血糖控制差；规律运动、戒烟、定期监测血糖、血脂达标的患者血糖控制较好。结论广东省大多数超重肥胖T2DM患者血糖控制未达标，迫切需要采取积极措施改善这一现况。
Objective To explore the glycemic control status and related risk factors of overweight or obesity patients with type 2 diabetes mellitus （T2DM） in Guangdong province. Methods The medical records of overweight or obesity patients with T2DM from 60 tertiary and secondary hospitals in Guangdong Province were collected by questionnaire and physical examination. And the clinical data were analyzed to explore the influencing factors of glyeemic control. The HbAlc level was used to assess glycemic control. HbAle 〈7.0% indicated that glycemie control was up to standard. Results From August 2011 to March 2012, 5241 T2DM patients were recruited. The scope of current analysis was restricted to 4768 subjects with true data and deficiency no more than 5%. There were 2252 males and 2516 females. The age range was from 16 to 90 years, a median age 59. 0 （50. 0 - 69. 0） years, onset age of diabetes 52. 0（44. 0 - 60. 0） years; a range of disease duration from 1 day to 42 years and a median of 5.0 （ 2. 0 - 11.0 ） years. The median body mass index was 26. 33 （ 24. 88 - 28. 34 ） kg/m2 and median waist circumference 93.0 （ 88.0 - 100.0） cm. Median HbAlc was 8.1% （6.9% - 10. 1% ） and only 26.2% patients reached the target level of HbAlc 〈 7.0%. Influencing factors of poor glycemic control were central obesity, high levels of resting heart rate, concurrent fatty liver and high intensity of treatment. And influencing factors of good glycemiccontrol were regular exercises, smoking cessation, regular glycemic monitoring and good control of total chloestrol/triglyceride. Conclusion A majority of Guangdong type 2 diabetics fail to achieve target values for glycemic control. There is an urgent need for comprehensive management for improving glycemic control.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2013年第2期104-109,共6页
National Medical Journal of China
基金
广东省肥胖及超重T2DM现况调查专项基金（粤医会[2011]229.1号）
关键词
糖尿病
2型
超重
肥胖
危险因素
Diabetes mellitus, type 2
Overweight
Obesity
Risk factors
