摘要
目的比较腹膜透析(PD)与血液透析(HD)改善肾性贫血的疗效。方法将31例尿毒症患者随机分为PD组(13例)和HD组(18例)。两组开始治疗时均未使用促红细胞生成素,治疗1个月后均加用促红细胞生成素,治疗2个月时均增加左卡尼汀联合促红细胞生成素进行治疗。比较分析两组患者透析前及透析后1、2、3个月的血红蛋白(Hb)变化。结果 PD组和HD组的Hb值在透析治疗前未见显著差异(P>0.05);两组Hb值在治疗1、2、3个月后与透析前比较显著升高P<0.01)。结论 PD和HD均能改善尿毒症贫血状态,而PD效果优于HD,促红细胞生成素对尿毒症导致肾性贫血状态有较好调节作用,联合左卡尼汀治疗效果更加明显。
Objective To compare the effect of peritoneal dialysis （PD） and hemodialysis （HD） on im- proving the renal anemia. Methods 31 cases of uremic patients were divided into two groups randomly, 13 cases of peritoneal dialysis（ PD group） , 18 cases of hemodialysis（ HD group）. The erythropoietin was not used at the beginning of the therapy, but added after 1 month of therapy, and the levocarnitine was combined with erythropoietin after 2 months of therapy. The hemoglobin （ Hb ） levels of pre-dialysis and 1,2 and 3 months post-dialysis of two groups were compared. Results Hb values of the two groups before dialysis was not significantly different（ P 〉 0.05 ）. Hb value after 1 month, 2 month, 3 months of treatment were signifi- cantly increased from the pre-dialysis（ P 〈 0.01 ）. Conclusion PD and HD can improve the state of anemia in uremia,and the effect of PD is superior to HD. Erythropoietin has a good regulating effect on the state of anemia induced by uremia, and the curative effect was more apparent when combined with levocarnitine.
出处
《医学综述》
2013年第2期368-369,共2页
Medical Recapitulate
关键词
慢性肾脏病
肾性贫血
血液透析
腹膜透析
Chronic kidney disease
Renal anemia
Hemodialysis
Peritoneal dialysis
