摘要
目的调查2000～2011年某三甲医院金黄色葡萄球菌临床分离株的耐药性变化趋势,为临床医生抗感染治疗提供依据。方法采用VITEK-32全自动细菌分析系统,GPS-119G药敏分析卡,药敏琼脂(M-H)均为法国梅里埃公司产品。用头孢西丁纸片扩散法(K-B法)进行抗菌药物活性试验。结果该院耐甲氧西林金黄色葡萄球菌(MRSA)的耐药率在71.1%～87.4%,同期医院感染菌耐药率在44.8%～87.5%,变化无明显规律性。结论耐药菌多年来居高不下,需规范使用抗菌药物、落实消毒隔离措施和提高手卫生依从性。
Objective To investigate the variation trend of drug resistance of the clinical isolated Staphylococcus aureus in a three A hospital during 2000-2011, and provide for clinicians the guidance of anti-infective therapy. Methods VITEK-32 automatic bacterial analysis system was applied with the GPS-119G drug susceptibility analysis card, drug sensitive testing agar （M-H） from Merieux France. The efficacy test of antibiotics was conducted with cefoxitin disk diffusion method （ K- B method）. Results The drug resistance rate of methicillin-resistant Staphylococcus aureus （MRSA） ranged t^om 71. 1% - 87.4% in the whole hospital, while that of the hospital infected bacteria was within 44.8%-87.5% over the same period and the change was irregular. Conclusion For a few years, the drug resistant bacteria keep high, it is necessary, to normalize antibiotics＂ application, carry out disinfection and quarantine measures, and improve hand hygiene compliance.
出处
《医药导报》
CAS
北大核心
2013年第1期26-28,共3页
Herald of Medicine
关键词
耐药性
耐甲氧西林金黄色葡萄球菌
金黄色葡萄球菌
Drug resistance
Methicillin-resistant Staphylococcus aureus （MRSA）
Staphylococcus aureus
