摘要
目的:探讨序贯应用米非司酮及米索前列醇终止瘢痕子宫早期妊娠的效果。方法:82例瘢痕子宫早孕要求终止妊娠患者,其中对照组56例直接行无痛人工流产;观察组26例序贯应用米非司酮及米索前列醇后行无痛人工流产。比较2组患者的镇痛效果、宫口扩张情况、术中出血量、丙泊酚用量、术后阴道流血时间、手术时间、宫腔残留、子宫穿孔等情况。结果:2组镇痛效果均为100%,观察组宫口100%扩张;观察组丙泊酚用量、手术时间、术后阴道流血时间均少于对照组(P<0.01);2组术中出血量、术后腹痛率与宫腔残留率差异均无统计学意义(P>0.05)。2组均无子宫穿孔发生。结论:米非司酮配伍米索前列醇应用于瘢痕子宫早孕终止妊娠安全有效,能减少子宫损伤、出血以及人工流产并发症。
Objective：To explore the effect of sequential administration of mifepristone and misoprostol in terminating early pregnancy in women with uterine scars. Methods： Eighty-two cases of early pregnancy that had uterine scars and required termination of pregnancy were divided into two groups. Fifty-six cases in control group were performed painless artificial abortion;26 cases in observation group were administered mifepristone and misoprostol in sequence. The analgesic effect, cervical dilation, blood loss, dosage of propofol, postoperative vaginal bleeding time, operation time, residual cavity and uterine perforation were compared between the two groups. Results：The analgesic effect of both groups was 100% ;The cervical dilation in the observation group reached 100%. The usage amount of propofol,operation time and postoperative vaginal bleeding in the observation group was less than those in the control group （ P 〈 0.01 ）. There was no significant difference between the two groups in the intraoperative blood loss ,rate of post-operative abdominal pain and rate of uterine residual （ P 〉 0.05 ）. No uterine perforation occurred in the two groups. Conclusions： Mifepristone combined with misoprostol is safe and effective in terminating early pregnancy in women with cicatricial uterus, as it can effectively reduce the uterine damage, bleeding volume and abortion complications.
出处
《蚌埠医学院学报》
CAS
2013年第1期63-65,共3页
Journal of Bengbu Medical College
