摘要
目的:探讨精神分裂症患者服用抗精神病药物前后血糖、甘油三酯及甲状腺素的变化情况。方法:选择精神分裂症患者60例,随机分为两组,A组口服氯氮平治疗,B组口服利培酮治疗,另选择健康体检者30例为对照,比较治疗前后患者血糖、甘油三酯及甲状腺素的变化情况。结果:两组治疗前后TG、FT4、TSH差异有显著统计学意义(P<0.05或P<0.01)。TG与FT3、FT4水平呈负相关。结论:抗精神病药物可导致精神分裂症患者血糖、血脂的异常,甘油三酯与甲状腺素水平呈负相关,治疗过程中应注意检测患者血糖血脂情况。
Objective：To discuss Change of levels of FBG,TG, thyroxine in patients with schizophrenia before and after treat- ment. Methods：Selected 60 cases with schizophrenia randomly divided into 2 groups. A group was treated with Clozapine, B group was treated with Risperidone. 30 healthy volunteers were selected as control group. Levels of FBG, TG and thyroxine were compared before and after treatment. Results： TG, FT4 and TSH had significant difference between before and after treatment in both group （ P 〈 0.05 or P 〈0.01 ）. There was a negative correlation between TG and FT3,FT4. Conclusions： Antipsychotics can lead to levels of FBG,TG abnormal, TG has a negative correlation with FT3, FT4. FBG,TG should be detected during treatment.
出处
《中国民康医学》
2013年第3期25-27,共3页
Medical Journal of Chinese People’s Health
