摘要
目的探讨各因素对血小板输注疗效的影响。方法以校正血小板计数增值(CCI)判定血小板输注效果,研究94例患者256人次输注血小板的疗效。将是否发热(X1)、脾大(X2)、使用抗菌药物(X3)、有活动性出血(X4)、反复输注血小板(X5)、病种和免疫因素有关(X6)、化疗进行中(X7)、血小板相关抗体阳性(X8)、血小板储存时间(X9)列入备选因素,对这些影响因素进行Logistic回归分析。结果经Logistic回归分析,发现X4、X8、X2、X5、X1、X6、X7、X3、X9为影响血小板输注疗效的独立风险因素,其OR值分别为2.527、2.430、2.036、2.000、1.450、1.345、1.128、1.080、1.005。结论血小板输注的疗效受多种因素影响,提高疗效最好的方法是避免或减少这些因素。
Objective To evaluate the influencing factors for curative effects of platelet transfusion. Methods The curative effects of 256 times platelet transfusion for 94 patients were studied by calculating modified platelet corrected count increment （CCI） as benchmark judging platelet transfusion refractoriness. The factors, including fever（X 1 ）, splenomegaly（ X2）, using antibiot- ic（X3）, bleeding state （ X4）, repeated transfusion （X5）, diseases correlated with immune factors （ X6 ）, chemotherapy （ X7 ）, platelet correlation antibody（XS）, platelet storage time（X9） were analyzed by binary logistic regression. Results The Logistic regression a nalysis results showed that X4, X8, X2, X5, X1, X6, X7, X3 and X9 were associated with platelet transfusion refractoriness, odds ra- tio（OR） values were 2. 527,2. 430,2. 036,2. 000,1. 450,1. 345,1. 128,1. 080 and 1.005,respectively. Conclusion The curative effects of platelet transfusion could be influenced by several factors, so it is necessary to avoid their occurrence.
出处
《国际检验医学杂志》
CAS
2012年第22期2719-2720,共2页
International Journal of Laboratory Medicine
关键词
血小板输注
疗效结果
回归分析
platelet transfusion
treatment atcome
regression analysis
