摘要
目的探讨奥美拉唑、阿莫西林联合克拉霉素三联疗法治疗胃溃疡的临床效果。方法选取本院2010年1月～2012年2月收治的78例胃溃疡患者,根据应用药物的不同将其分为观察组和对照组各39例,评价两组患者的临床疗效及不良反应情况。结果观察组的治疗总有效率为100.00%,明显高于对照组的89.74%;治疗后炎症变化及溃疡修复情况观察组明显优于对照组,差异有统计学意义(P<0.05);不良反应总发生率观察组与对照组差异无统计学意义(P>0.05)。结论经治疗后两组患者的黏膜炎症、外凸皱襞、溃疡面积均有不同程度的改善,但观察组效果明显优于对照组,可达到根治效果,应于临床推广应用。
Objective To investigate the clinical effects of omeprazole, amoxicillin combined with clarithromycin as a triple therapy in the treatment of gastric ulcer. Methods According to the application of different drugs, 78 patients with gastric ulcer admitted into our hospital from January 2010 to February 2012 were evenly divided into two groups： observation group and control group. The clinical effects and the situation of adverse reaction were evaluated in both groups. Results The total effective rate in observation group reached up to 100.00%, which was obviously higher than that in control group （89.74%）. After treatment, inflammatory changes and ulcer repair in observation group were remarkably superior to those in control group with a statistical difference （P 〈 0.05）. The incidences of adverse reaction in both groups showed no significant difference （P 〉 0.05）. Conclusion The mueosal inflammation, outer convex plica, ulcer area in the two groups after treatment both has improvements to certain degrees, but the clinical effects in obser- vation group are significantly superior to those in control group, which can be cured radically and deserve extensive application in clinic.
出处
《中国当代医药》
2013年第3期86-87,共2页
China Modern Medicine
