摘要
目的探讨恰当地预防性应用抗生素的方法。方法选取2008年2月～2012年1月到本院普外科接受手术治疗的患者130例作为研究对象。将所有患者根据抗生素选择的种类不同分成青霉素类组、头孢菌素类组和喹诺酮类组,然后根据切口和给药类型进行再分类。观察并记录患者切口感染发生率。结果在Ⅰ类切口患者中,3组切口感染发生率差异无统计学意义(P>0.05);而在Ⅱ、Ⅲ类切口中,青霉素类组的切口感染发生率显著高于头孢菌素类组和喹诺酮类组,差异有统计学意义(P<0.05);而头孢菌素类组和喹诺酮类组在Ⅱ、Ⅲ类切口间的感染发生率差异无统计学意义(P>0.05)。结论普外科手术时应根据患者手术、切口类型和患者个体差异选择适当的预防性抗菌药物,避免过分依赖抗生素和耐药菌的出现,合理配置药物资源,减轻患者费用和机体的负担,最终实现临床最优的治疗效果。
Objective TO explore an appropriate method of prophylactic antibiotics. Methods One hundred and thirty cases of patients in general surgery department of our hospital from February 2008 to January 2012 were selected as research objects. They were divided into three groups according to different kinds of antibiotics. They were the penicillin group, the cephalosporin group and quinolones group. The three groups were divided into different groups according to the type of incision and pharmacy. The infection rate of incision was recorded. Results In the incision of I , the difference between three groups was not statistically significant （P 〉 0.05）. In the incision of I1 and II1, the infection rate of incision in penicillin group was obviously higher than the other two groups, the difference was statistically significant （P 〈 0.05）, the difference of the infection rate in the cephalosporin group and quinolones group was not statistically significant （P 〉 0.05）. Conclusion Prophylactic antibiotics should be used appropriately according to the types of operation, incision and individual differences of patients. We should avoid the incidence of undue dependence of antibiotics and depose the resource of drug reasonable to reduce the burden of patient. By this way, we can achieve the best effect of treatment in the clinic.
出处
《中国当代医药》
2013年第6期49-50,共2页
China Modern Medicine
关键词
抗生素
普外科
切口感染
合理用药
Antibiotics
General surgery department
Infection.0f incision
Rational drag use
