期刊文献+

同源异体富血小板凝胶治疗糖尿病足溃疡的疗效 被引量:20

The treatment of diabetic foot ulcer with allogeneic platelet gel
在线阅读 下载PDF
导出
摘要 目的探讨同源异体富血小板凝胶治疗糖尿病足溃疡的疗效。方法将60例糖尿病足患者随机平均分为观察组和对照组,对照组30例采用常规外科换药方法,观察组30例采用异体血小板凝胶治疗。观察两组治疗前后的溃疡面积收缩率、肉芽百分比、愈合时间及疼痛感的变化。结果观察组痊愈率70%,有效率100%,显著高于对照组。观察组溃疡面积缩小率、肉芽覆盖率显著高于对照组,愈合时间显著短于对照组(P<0.01)。结论同源异体富血小板凝胶治疗能够有效促进糖尿病足溃疡的愈合,缩短创面愈合时间,减少医疗成本和减轻患者痛苦,简单易行、有效。 Objective To study the efficacy of allogenic platelet gel on treatment of patients with diabetic foot ul- cer. Methods Sixty patients with diabetic foot ulcer were randomly divided into experimental group and control group, in which allogenic platelet gel on raw surface and Vaseline bandage were given, respectively. The therapeutic efficacy, the average healing time were be recorded. Results The therapeutic efficacy in experimental group was significantly better than that in control group, with significantly shortened healing time. Conclusion Therapeutic effect of allogenic platelet gel on diabetic foot ulcer is excellent.
出处 《广东医学》 CAS CSCD 北大核心 2013年第1期129-131,共3页 Guangdong Medical Journal
基金 广东省科技计划项目(编号:2009B080701092)
关键词 糖尿病足溃疡 同源异体富血小板凝胶 创面愈合 diabetic foot ulcer allogeneie platelet gel healing effect
  • 相关文献

参考文献10

  • 1KHAN OLKAR M P,BAIN S C,STEPHENS J W. The diabetic foot[J].Quarterly Journal of Medicine,2008,(09):685-695.doi:10.1093/qjmed/hcn027.
  • 2何利平,冉兴无.糖尿病足的诊治进展[J].内科急危重症杂志,2008,14(4):171-173. 被引量:11
  • 3BOULTON AJM. Foot problems in patient s with diabetes mellitus[A].London:blackwell,1997.1-20.
  • 4洪庆山,薛耀明,高方,韩亚娟.计算机图像技术在糖尿病创面定量研究的应用[J].中华损伤与修复杂志(电子版),2009,4(1):18-20. 被引量:15
  • 5袁南兵,王椿,王艳,余婷婷,舒世清,刘敏,冉兴无.自体富血小板凝胶在糖尿病难治性皮肤溃疡中的初步应用[J].四川大学学报(医学版),2007,38(5):900-903. 被引量:52
  • 6COOPER D M,YU E Z,HENNESSEY P. Determination of endogenous cytokines inchronic wounds[J].Annals of Surgery,1994,(06):688-692.
  • 7SZABO S,VINCZE A. Growth factors in ulcer healing:lessons from recent studies[J].The Journal of Physiology,2000,(02):77-81.
  • 8DRIVER V R,HANF T J,FYLLING C P. A prospective,randomized,controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers[J].Ostomy Wound Management,2006,(06):68-74.
  • 9AMINIAN B,SHANIS M,SOVEYD M. Topical autologous platelet-derived growth factors in the treatment of chronic diabetic ulcers[J].Arch Iran Med April,2000,(01):37-40.
  • 10PERSEGHIN P,SCIORELLI G,BELOTTI D. Frozen-and-thawed allogeneic platelet gels for treating postoperative chronic wounds[J].Transfusion,2005,(09):1544-1546.

二级参考文献38

共引文献73

同被引文献170

引证文献20

二级引证文献255

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部