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淋巴结转移数与淋巴结转移率对胃癌预后影响的比较研究 被引量:4

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摘要 目的评价淋巴结转移数(NLMN)与淋巴结转移率(RLMN)对胃癌患者预后的评估价值。方法回顾性分析98例行胃切除术胃癌患者的临床资料,应用受试者工作特征(ROC)曲线对NLMN及RLMN进行分析,得出各自临界值,并以此临界值进行生存分析,比较临界值上下的5年生存率。结果ROC曲线显示NLMN的临界值为5个[敏感度为85.8%,特异度为91.1%,ROC曲线下面积(AUC)为0.91],RLMN的临界值为21.5%(敏感度为83.9%,特异度为49.3%,AUC为0.69),NLMN的敏感度及特异度均高于RLMN(P〈0.05)。进一步生存分析显示NLMN〈5个和≥5个的患者生存时间分别为63.2—65.5(64.4±0.6)个月和53.8~60.6(57.2±1.8)个月;5年生存率分别为87.0%(20/23)和62.7%(47/75),NLMN〈5个患者的5年生存率高于NLMN35个患者,差异有统计学意义(P〈0.05);RLMN〈21.5%和321.5%的患者生存时间分别为62.2。65.5(63.9±0.8)个月和53.8—63.2(61.1±1.1)个月;5年生存率分别为80.4%(41~1)和55.3%(26/47),RLMN〈21.5%患者的5年生存率高于RLMN≥21.5%患者,差异有统计学意义(P〈0.01)。结论NLMN相对于RLMN对胃癌预后的评估价值更为可靠。
作者 李晶 骆成玉
出处 《中国医师进修杂志》 2013年第3期64-66,共3页 Chinese Journal of Postgraduates of Medicine
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