摘要
了解引起肝胆疾病腹腔感染的主要病原菌及其对抗生素的耐药性,为临床用药提供参考。对2011年3月到2012年10月期间115例腹腔感染的患者腹腔引流液细菌培养及药敏试验进行分析。细菌阳性率为75.7%,90株微生物包括14种细菌和1种真菌。革兰阳性菌占12.2%;革兰阴性菌占84.4%;白色念珠菌占3.3%。革兰阴性菌,主要菌群为:大肠埃希菌占30%;肺炎克雷伯杆菌占24.4%;铜绿假单胞菌占8.9%;溶血不动杆菌占5.6%。革兰阳性菌中,葡萄球菌占8.9%,肠球菌占3.3%。革兰阴性菌对二、三代及部分四代头孢菌素和喹诺酮类耐药率较高;革兰阳性菌对喹诺酮类耐药率最高。肝胆外科感染性疾病中革兰阴性菌仍占主导地位,对常用的抗生素产生了不同程度的耐药,在治疗肝胆外科感染疾病时应常规进行引流液细菌培养加药敏试验,根据结果合理应用抗生素。
To provide a reference for the clinical use of drugs by studying the chief pathogens causing intra-abdominal in- fection and their antibiotic resistance. The data of bacterial culture of drainage fluid （collected from preoperative and post- operative patients） were studied in 115 patients with intra-abdominal infections admitted from march 2011 to October 2012 and their sensitivity to antibiotic were analyzed. The positive rate of bacterial culture was 75.7%, and there were 90 strains of microbes belonging to 15 species, including 14 bacterial and 1 fungal. Gram-positive bacteria accounted for 12.2% , Gram-negative bacteria accounted for 88.4%, and Candida albicans 3.3%. For Gram-negative bacteria, the main flora were Escherichia coli 30%, Klebsiella pneumoniae 24.4%, Pseudomonas aeruginosa 8.9%, Acinetobacter he- molytic 5.6 %. For Gram-positive bacteria, Staphylococcus 8.9% and Enterococcus 3.3 %. Gram-negative bacteria had high resistant rate to the second, third even fourth generation cephalosporins, and quinolones; gram-positive bacteria had highest resistant rate to quinolones. Gram-negative bacteria are still dominating in intra-abdominal infection. Infection flora has different levels of resistance to commonly used antibiotics. During the treatment of abdominal infection, culture and susceptibility test of drainage fluid should be routinely clone and antibiotics should be used accordingly.
出处
《医学与哲学（B）》
2013年第1期37-39,共3页
Medicine & Philosophy(B)
基金
吴阶平医学基金会临床科研专项资助基金
项目编号:320.6750.1281
辽宁省教育厅课题
项目编号:L2011145
关键词
腹腔感染
引流液
细菌培养
药敏
intra-abdominal infection, fluid drainage, bacterial culture, drug sensitivity
