摘要
目的:评价肿瘤标志物肿瘤特异性生长因子(TSGF)、血清糖抗原19-9(CA19-9)、血清糖抗原125(CA125)对消化道恶性肿瘤的诊断价值,以及联合检测的临床意义。方法:受检者包括消化道肿瘤患者102例,其中肝癌31例,胃癌27例,食管癌16例,结直肠癌17例,胰腺癌11例。消化系良性疾病患者57例,其中肝硬化23例,良性非肝病34例。健康查体20例。联合检测TSGF、CA19-9、CA125。结果:消化道恶性肿瘤患者的TSGF、CA19-9、CA125水平高于肝硬化组(TSGF除外)、非肝病组及健康组(P<0.01)。上述3指标对消化道肿瘤诊断的敏感性分别为69.6%、58.8%、53.9%。三者联合检测对消化道恶性肿瘤诊断的敏感性可提高为92.2%。结论:TSGF、CA19-9、CA125均为较好的消化道恶性肿瘤标志物,联合检测效果更佳。
Objective:To evaluate the diagnostic value of tumor specific growth factor(TSGF), serum carbohyrate antigen 19-9 (CA19-9),and CA 125 in diagnosing digestive neoplasms. Methods:TSGF,CA19-9 and CA125 were simultaneously detected in 31 liver cancer patients,27 gastric carcinoma,16 esophageal carcinoma,17 colorectal carcinoma,11 pancreatic carcino ma,23 hepatic cirrhosis,34 benign non-liver disease,and 20 healthy persons. Results:TSGF,CA19-9,and CA125 in digestive neoplasm group were significantly higher than that in hepatic cirrhosis (except TSGF), non-liver disease and healthy group(P<0.01). The diagnostic sensitivity of TSGF,CA19-9,and CA125 in digestive neoplasm was 69.6% ,58.8% ,and 53.9% respectively,and the sensitivity with combined detection was 92.2% . Conclusion:Serum TSGF,CA19-9,CA125 are better markers for diagnosis of digestive neoplasm with better results from combined detection.
出处
《天津医药》
CAS
2000年第10期587-589,共3页
Tianjin Medical Journal
关键词
消化道肿瘤
诊断
肿瘤特异性生长因子
neoplasms growth substances digestive system neoplasms antigens, tumor-associated,carbohydrate
