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灵芝多糖锗的抗肿瘤及免疫增强作用研究 被引量:44

Study on Effects of Saccharum Germanium of Glossy Ganoderma on Immunity and Antitumor
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摘要 目的 :研究灵芝多糖锗对实验性肉瘤和腹腔巨噬细胞活性的影响。方法 :利用接种肉瘤S180 腹水型诱导的小鼠肿瘤模型 ,检测对S180 肉瘤的抑制率 ;利用酸性磷酸酶测定法 ,检测对荷瘤小鼠腹腔巨噬细胞活性的影响。结果 :灵芝多糖锗可抑制小鼠S180 肉瘤的生长 ,能增强荷瘤小鼠腹腔巨噬细胞的活性。结论 :灵芝多糖锗具有抗肿瘤及免疫增强活性。 Purpose:To study the effects of saccharum germanium of glossy ganoderma on experimental sarcoma and on the activity of rhagiocrine cells in abdomial cavity.Methods:By vaccinating ascites inducing mouse′s tumor model of sarcoma,the rate of inhibition of saccharum germanium of glossy ganoderma on the sarcoma was tested.By using the determination of acid phosphatase, the effects of the activity of rhagiocrine cell in the abdominal cavity of the mouse that caught tumor were tested.Results:The compound of saccharum germanium of glossy ganoderma may inhibit the mouse′s sarcoma from growing and increase the activity of rhagiocrine cells in the abdominal cavity of rhagiocrine cells in the abdominal cavity of the mouse that caught tumor.Conclusion:Saccharum germanicim of glossy ganoderma can resist tumour and increase the immunological activity.
作者 牛建伟 谢平
出处 《中国生化药物杂志》 CAS CSCD 2000年第4期189-190,共2页 Chinese Journal of Biochemical Pharmaceutics
关键词 灵芝多糖锗 肿瘤抑制率 巨噬细胞活性 药理 Saccharum germanium of glossy ganoderma, Inhibition rate of tumour, Rhagiocrine cell
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参考文献4

  • 1徐淑云 卞如濂.药理实验方法学[M].北京:人民卫生出版社,1982.524-527,614-616.
  • 2林飞卿 匡彦德 等.小鼠巨噬细胞激活状态的测定--三种测定法的比较[J].中华微生物和免疫学杂志,1981,1(4):274-278.
  • 3徐淑云,药理实验方法学,1982年,1115页
  • 4林飞卿,中华微生物学和免疫学杂志,1981年,1卷,4期,274页

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