摘要
目的探讨Narcotrend脑电/意识深度监测(NT指数)指导下调控婴儿先天性心脏病外科手术麻醉深度的可行性和有效性。方法选择择期行先天性心脏病矫治术患者80例(ASAⅡ～Ⅲ级),采用随机数字表法,将患者随机分为2组,N组(n=40):NT指数指导下进行麻醉用药与调控;C组(n=40):隐蔽NT指数监测,由麻醉科医师按传统经验调节麻醉用药。常规监测ECG、HR、SpO2、桡动脉压、右颈内静脉中心静脉压(CVP)及NT指数,记录NT指数、术中麻醉用量、苏醒时间、拔除气管导管时间和可能发生的不良反应;结果 NT指数波动较小,N组镇静药量、镇痛药量及肌松药用量比C组明显减少(P<0.05),苏醒时间提前3～4 h;拔除气管导管提前7～8 h(P<0.05),两组不良反应无统计学差异。结论婴儿先天性心脏病外科手术应用NT麻醉深度监测系统安全有效,可使麻醉深度达到量化,个体指数明确,麻醉深度直观明确,是一种连续实时无创的脑电/意识深度监测方法供临床选用。
Objective To investigate the feasibility and effectiveness of Narcotrend electroencephalogram （EEG）/consciousness depth monitor （NT index） for adjusting anesthesia depth in congenital heart disease （CHD） infants receiving surgeries. Methods A total of 80 CHD infantsd （ASA Ⅱ- Ⅲ） to be subjected to surgery were randomly selecte and assigned into two groups randomly. In the N group （n=40）, the depth of anesthesia was monitored with NT index; in the C group （n=40）, the anesthesia depth was controlled according to the anesthetist＇s experience without NT index. The ECG, HR, SpO2, the mean arterial pressure of left radioartery, the central venous pressure （CVP） of right cervical vein and NT index were monitored routinely. The NT index, total dose of anesthesia drugs, recovery time, extubation time and possible badness reaction were determined. Results NT index waved less, the dosage of sedative and analgesic drugs and muscle relaxant medicinal volume of the N group decreased significantly than the C group （P〈0.05）, the recovery time was 3 to 4 hours ahead and the extubation time was 7 to 8 hours in advance （P〈0.05）. There was no statistically significant differences between the two groups in adverse reactions. Conclusion The Narcotrend anesthesia depth monitor is safe and beneficial for the control of anesthesia depth in CHD infants receiving surgeries in which anesthesia depth can be quantized, the index and the anesthesia depth is definited in quantity. The Narcotrend EEG/consciousness monitor can supply a continuous,non-traumatic and real-time monitor for clinical anesthesia.
出处
《实用医药杂志》
2013年第3期199-201,共3页
Practical Journal of Medicine & Pharmacy
