摘要
目的探讨小儿先天性心脏病(先心病)患儿术后,中心静脉导管相关血流感染(CLA-BSI)发生水平及病原菌分布特点。方法对2012年1-12月心脏病治疗中心手术治疗的928例先心病患儿进行CLA-BSI目标性监测,将中心静脉导管留置时间>48h或拔除导管<48h内的先心病术后患儿作为研究对象,对CLA-BSI发生水平和病原菌检出进行分析。结果共诊断CLA-BSI病例15例,感染率为1.62%,每千个导管日感染为3.79‰;经外周静脉血或(和)中心静脉导管尖端标本共检出病原菌23株,病原菌以革兰阴性菌为主,不动杆菌属、铜绿假单胞菌以及褪色沙雷菌居前3位。结论先心病患儿是CLA-BSI高危人群,应加强术后先心病患儿CLA-BSI的监测和干预措施,减少医院感染的发生。
OBJECTIVE To investigate the incidence of the central venous catheter-associated bloodstream infections in the children with congenital heart disease （CHD） after cardiac surgery and observe the distribution of pathogens. METHODS The targeted surveillance was performed for 928 children with CHD who were treated in the cardiac ICU from Jan to Dec 2012, and the children with the indwelling catheter duration over 48 hours and the children with the extubation time less than 48 hours were selected as the study objects, then the incidence of the central venous catheter--related bloodstream infections and the isolation of pathogens were analyzed. RESULTS Totally 15 cases were diagnosed as the central venous catheter-related bloodstream infections with the incidence of 1.62% and 3.79/1. 000 catheter days; totally 23 strains of pathogens were isolated from peripheral vein blood and/or catheter tips, which were mainly the gram-egative bacteria, and the Acinetobacter baumannii, Pseudo- rnonas aeruginosa and Serratia marcescens were the top three species. CONCLUSION The children with CHD are at high risk of the central-venous catheter-related bloodstream infections, it is necessary to strengthen the surveil- lance of the central venous catheter-related bloodstream infections in the children after cardiac surgery and take interventions so as to reduce the incidence of nosocomial infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第7期1598-1599,1626,共3页
Chinese Journal of Nosocomiology
关键词
小儿先天性心脏病
手术
中心静脉导管相关血流感染
Congenital heart disease
Surgery
Central venous catheter-related bloodstream infection
