摘要
目的探讨踝肱指数(ABI)异常的2型糖尿病(T2DM)患者发生糖尿病足的危险因素。方法 ABI<0.9的T2DM患者74例分为未发生糖尿病足(A组,61例)和发生糖尿病足(B组,13例)两组,分析发生糖尿病足的危险因素。结果单因素分析显示,A组糖尿病病程、吸烟史、收缩压、触觉及痛觉阈值、空腹血糖、糖化血红蛋白及糖化血清蛋白均低于B组(P<0.05或P<0.01),A组载脂蛋白A1高于B组(P<0.05)。多因素非条件Logistic回归分析显示,吸烟和空腹血糖是糖尿病足发生的独立危险因素(P<0.05)。结论在糖尿病足的预防工作中应重视加强对糖尿病患者的健康宣教,积极控制高血糖,并劝告戒烟。
Objective To investigate the risk factors for diabetic foot in type 2 diabetes mellitus （T2DM） patients with abnormal ankle-brachial index（ABI）. Methods The risk factors for diabetic foot in T2DM patients with ABI〈0. 9 were analyzed, who were divided into two groups of A（61 cases,without diabetic foot） and B（13 cases,with diabetic foot）. Results The duration of diabetes, history of smoking,systolic blood pressure, threshold of touch and pain sensation, fasting blood glucose, glycosylated hemoglobin values were all higher in group B than those in group A（P〈0. 05 or P〈0. 01）. Multivariate unconditional logistic regression analysis showed that smoking and fasting blood glucose levels were the independent risk factors for diabetic foot in T2DM patients with ABI〈（ 0. 9（P〈0. 05）. Conclusion To prevent the diabetic foot in T2DM patients with ABI〈0. 9, attention should be paid to strenthening health education for diabetes, controlling hyperglycemia, and encouraging Stopping smoking.
出处
《江苏医药》
CAS
北大核心
2013年第7期821-823,共3页
Jiangsu Medical Journal
基金
江苏省自然科学基金(BK2012651)
关键词
糖尿病足
2型糖尿病
踝肱指数
Diabetic foot
Type 2 diabetes mellitus
Ankle-brachial index
