摘要
白介素-17(IL-17),CD4+细胞亚群Th17细胞分泌的特征性细胞因子,在抵抗胞外细菌、真菌感染的宿主防御以及各种自身免疫性疾病发病中起到了重要作用。绝经后骨质疏松现被认为可能是一种炎症过程,现有研究表明IL-17在绝经后骨质疏松的发病机制中具有重要作用。本文综述了近几年IL-17在绝经后骨质疏松相关研究中的研究进展,为后续相关研究提供理论支撑。
Interleukin-17 （IL-17） , which is the characteristic cytokine secreted by Thl7 cells of CD4＋ eel1 subset, plays an important role in the process of host defense, such as resisting the extracellular bacterial and fungal infection and a variety of autoimmune diseases. Postmenopausal osteoporosis is now thought to be an inflammatory process. Studies have revealed that IL-17 plays an important role in the pathogenesis of postmenopausal osteoporosis. This paper reviews the research progress of the effect of IL-17 on postmenopausal osteoporosis in recent years, in order to provide theoretical support for the follow-up study.
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2013年第3期310-313,共4页
Chinese Journal of Osteoporosis
