摘要
目的评价联合检测降钙素原（PCT）与C反应蛋白（CRP）水平的改变在高海拔地区细菌感染患者中的临床意义。方法随机收集2008年10月~2011年9月入住青海大学附属医院重症监护病房（ICU）的83例细菌感染患者血清PCT与CRP的含量及动态变化进行检测,同时将83例细菌感染患者分为重症感染组47例和局部感染组36例,并与30例非感染组进行分析比较。结果治疗前感染组血清PCT、CRP水平较非感染组明显升高,经积极有效的抗菌药物治疗后,感染组血清PCT与CRP水平较治疗前明显降低,差异有显著性（P〈0.01）。结论血清PCT与CRP联合检测在细菌感染的早期诊断中有一定价值,动态监测PCT与CRP水平有助于评估治疗效果,协助临床判断病情的转归和恶化。
【Objective】To evaluate the clinical significance in evaluating prognosis of the combined determination of serum procalcitionin（PCT） and C reactive protein（CRP） in the diagnosis of bacterial features in intensive care unit of the high elevation area.【Methods】83 patients in Affiliated Hospital Of Qinghai University,from 2008 to 2011 with bacterial infection were enrolled in the studies which were classified into serious infection group and local infection group.Serum PCT and CRP levels and their dynamic change were measured,and the results were analyzed and compared with those non-infection group.【Results】The mean values of PCT and CRP in infection group were statistical significance compared to non-infection group.After the antibiotic treated,the levels of PCT and CRP decreased significantly;the levels of PCT and CRP in serious infection group were statistical significance to local infection group（P 0.001）.【Conclusion】The combined determination of PCT and CRP assists the early diagnosis and prognosis of bacterial in neonate,Monitoring and dynamically PCT level will help to evaluate the curative effect.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2013年第6期66-68,共3页
China Journal of Modern Medicine
关键词
降钙素原
C反应蛋白
细菌感染
高海拔地区
procalcitionin
C-reactive protein
bacterial features
high elevation area
