摘要
目的研究在急性主动脉综合征(AAS)患者血清中超敏C反应蛋白(hs-CRP)的鉴别诊断价值。方法选取54例诊断为急性主动脉综合征的患者,将其分为主动脉夹层分离(AD)、主动脉壁内血肿(IMH)和穿透性粥样硬化主动脉溃疡(PAU)三组,并在入院治疗前检测血清中hs-CRP浓度,使用Kruskal-Walis非参数检验、卡方检验或Fisher′s精确检验判断各组间的差异,同时对hs-CRP进行受试者工作者曲线(ROC)分析其在AAS鉴别诊断中的敏感度、特异度。结果 hs-CRP在AD组有较高的水平,同时其浓度为12.21mg/L时有较好的诊断价值,曲线下面积(AUC)为0.83,敏感度为91.2%,特异度为69.2%。结论 hs-CRP水平检测可以作为急性主动脉综合征的一个鉴别诊断指标。
Objective The purpose of this study was to determine whether high-sensitivity C-reactive protein（hs-CRP） levels differ among patients with acute aortic syndromes（AAS）. Methods 54 Patients who were included in the study had measurement of serum levels of Hs-CRP. The patients were grouped into aortic dissection（AD）,intramural haematoma（IMH） and penetrating aortic ulcer（PAU）. Kruskal-Wallis non-parametric analysis, x2 tests and Fisher＇s Exact Test were used to analyse group differences for the continuous data. The sensitivity and specificity of hs-CRP in the diagnosis of ASS were performed using receiver-operating characteristic curve. Results The level of hs-CRP was the highest in AD patients than others. The area under the curve for hs-CRP was 0.83 and the cut-off level of hs-CRP of 12.21 mg/L yielded a sensitivity of 91.2% and specificity of 69.2%. Conclusion Raised hs-CRP level can be used as an index of differential diagnosis in patients with AAS.
出处
《国际检验医学杂志》
CAS
2013年第8期957-958,共2页
International Journal of Laboratory Medicine
