摘要
目的:分析老年慢性阻塞性肺疾病与继发性骨质疏松症的相关性。方法:选择我院收治的54例老年慢性阻塞性肺疾病患者为实验组及38例同期在我院治疗的肺功能正常的非COPD患者为对照组,分析和比较其腰椎(L1-4)和股骨近端的骨密度、肺功能、血气以及血钙、磷等生化指标。结果:实验组腰椎(L1-4)和股骨近端的骨密度均显著低于对照组。不同严重程度的COPD患者骨质疏松的发生率均显著高于对照组,且随着COPD患者病情严重程度的增加,骨质疏松的发生率逐渐上升。实验组骨密度的降低与PaO2的变化呈显著正相关。结论:老年慢性阻塞性肺疾病患者易发生骨质疏松,低氧血症可能是其并发骨质疏松的重要危险因素之一。
Objective： To explore the relationship between chronic obstructive pulmonary disease （COPD） in senior and osteoporosis. Methods： 54 patients of COPD and 38 cases ofnon-COPD with normal lung function admitted at same time were selected as the experimental group and control group respectively, the bone density of vertebra （L1-4） and proximal femur, change of lung function, arterial blood gas and biochemical markers such as Ca^2＋ were detected and compared. Results： Compared with the control group, the BMD of experimental group in lumbar vertebra （L1-4） and proximal femur was significantly lower, while the incidence of osteoporosis in experimental group was significantly higher. With the increase in severity of COPD patients, the incidence of osteoporosis gradually increased. The reduction of BMD in experimental group was positively correlated with PaO2. Conclusion： Chronic obstructive pulmonary disease may promote the development ofosteoporosis, meionectic blood might be the important risk factor.
出处
《现代生物医学进展》
CAS
2013年第9期1736-1738,共3页
Progress in Modern Biomedicine
关键词
慢性阻塞性肺疾病
骨质疏松
骨密度
Chronic obstructive pulmonary disease
Osteoporosis
Bone density
