摘要
原发性醛固酮增多症(PA)曾被认为是一种罕见疾病,随着血浆肾素活性检查技术的提高,ARR普遍被采用,其检出率较以前显著提高。但是ARR受多种因素的影响,并且各个医疗中心所使用的检测方法、筛查人群的种族、体位及筛查前是否停用药物等因素不一致,因此各家报道的ARR切点也不尽相同。因此本文就ARR及其影响因素和近年来ARR切点的相关研究进行综述,以提高ARR筛查PA的准确率。
Primary hyperaldosteronism used to be a kind of rare disease. With the measurement technique for plasma lenin activity increased and ARR widespreadly used,the detection rate of PA was significantly elevated. But, because ARR was affected by some factors, such as measurement technique, populations, positions and stopping antihypertensive drugs or not, various medical centre reported different ARR cutoff values. Therefore, the primary objective of this article was to review ARR,influencing factors and recent researches about it~ cutoff values to elevate the accuracy of PA screening.
出处
《农垦医学》
2012年第6期522-524,共3页
Journal of Nongken Medicine
关键词
醛固酮
肾素比值
原发性醛固酮增多症
plasma aldosterone concentration to plasma renin activity ratio
Primary hyperaldosteronism