期刊文献+

布地奈德联合特布他林雾化吸入治疗毛细支气管炎162例疗效观察 被引量:6

Clinical Efficacy of Budesonide plus Terbutaline for Bronchiolitis:Observation of 162 Cases
在线阅读 下载PDF
导出
摘要 目的:观察布地奈德联合特布他林雾化吸入治疗毛细支气管炎的临床疗效。方法:将162例毛细支气管炎患儿以随机抽样法分成对照组80例和治疗组82例。2组患者均常规给予抗感染、抗病毒、平喘、化痰、吸氧等治疗,治疗组在此基础上加用布地奈德混悬液联合特布他林雾化液气泵雾化吸入,比较2组疗效并进行统计学处理。结果:治疗组患者在咳嗽消失、喘憋缓解、哮鸣音和肺部啰音消失时间、病程缩短方面明显优于对照组(P<0.01);治疗组(治愈率为93.90%)疗效优于对照组(治愈率为61.25%)(P<0.01)。结论:布地奈德联合特布他林雾化吸入治疗毛细支气管炎疗效好,值得临床推广。 OBJECTIVE:To observe the clinical efficacy of budesonide plus terbutaline (aerosol inhalation) for bronchiolitis. METHODS: 162 pediatric patients with bronchiolitis were randomly divided into control group (n = 80) and trial group ( n = 82 ). Both groups received anti-infective, antiviral, antiasthmatic, phlegm-dissipating therapy plus oxygen inhalation; however, the trial group was administered with add-on budesonide suspension plus terbutaline atomized liquid (aerosol inhalation). The clinical efficacy was compared between the two groups and the data were treated statistically. RESULTS: The trial group was significantly better than the control group with regard to the extinction time of cough, wheezing and lung rales, relief of asthmatic suffocation, shortening of course of treatment (P 〈0. 01) and the cure rate in the trial group was higher than in the control group (93.90% vs. 61.25% ) (P 〈 0. 01). CONCLUSION: Budesonide combined terbutaline (aerosol inhalation) was proved to be of good clinical efficacy for bronehiolitis and thus the therapy is worth of clinical popularization.
出处 《中国医院用药评价与分析》 2013年第4期363-365,共3页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 特布他林 布地奈德 毛细支气管炎 雾化吸入 Terbutaline Budesonide Bronchiolitis Aerosol inhalation
  • 相关文献

参考文献9

二级参考文献32

  • 1陈艺平,黄飘,陈英女.雾化吸入喘乐宁治疗儿童哮喘的观察与护理[J].中国实用护理杂志,2006,22(4):28-29. 被引量:26
  • 2江培春,朱彤.中西医结合治疗小儿毛细支气管炎38例[J].国医论坛,2007,22(3):41-41. 被引量:3
  • 3李桂萍.普米克令舒与沙丁胺醇雾化吸入治疗毛细支气管炎疗效观察[J].中华现代儿科杂志,2006,3(3):261-262.
  • 4Bousquet J, Jeffery PK, Busse WW, et al. Asthma. From bronchoconstriction to airways inflammation and remodeling[J]. Am J Respir Crit Care Med, 2000; 161 (5) :1 720.
  • 5Szefler S J, Lyzell E, Fitzpatrick S, et al. Safety profile of budesonidc inhalation suspension in the pediatric population: worldwide experience [ J ]. Ann Allergy Asthma lmmunol, 2004, 93(1): 83.
  • 6Vaghi A, Berg E, Liljedahl S, et al. In vitro comparison of nebulised budesonide (Pulmicort Respules ) and beclomethasone dipropionate[ J]. Pulm Pharmacol Ther , 2005, 18(2): 151.
  • 7Tinkelman DG, Bronsky EA, Gross G, et al. Efficacy and safety of budesonide inhalation powder (Pulmicort Turbuhaler) during 52 weeks of treatment in adults and children with persistent asthma[ J]. J Asthma, 2003 ,40 (3) :225.
  • 8Song IH, Buttgereit F. Non-genomic glueocorticoid effects to provide the basis for new drug developments [ J ]. Mol Cell Endocrinol, 2006,246 ( 1 - 2 ) : 142.
  • 9Mendes ES, Pcreira A, Danta I, et al. Comparative bronchial vasoconstrictive efficacy of inhaled glueocorticosteroids[ J]. Eur Respir J,2003,21(6) :989.
  • 10Powell CE, Watson CS, Gametchu B. Immunoaffinity isolation of native membrane glucocorticoid receptor from S -49 + + lymphoma cells: biochemical characterization and interaction with Hsp 70 and Hsp 90[ J]. Endocrine, 1999,10(3) :271.

共引文献766

同被引文献38

二级引证文献49

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部