摘要
目的研究血清叶酸和VB2水平与食管癌的关系。方法采用酶联免疫吸附法测定1∶1∶1配对的106例食管癌患者、106例食管癌前病变患者和106例正常对照组血清叶酸和VB2水平。结果食管癌组与食管癌前病变组的血清叶酸、VB2水平均低于正常组(P<0.05);食管癌组的血清叶酸水平均低于食管癌前病变组(P<0.05),而食管癌组与食管癌前病变组的血清VB2水平的差异无统计学意义(P>0.05)。结论叶酸和VB2的缺乏与食管癌的发生、发展有关。
Objective To study the relationship between serum folic acid and VB2 levels and esophageal cancer.Method The enzyme-linked immunosorbent assay was used to observe the serum folic acid and vitamin B2 levels of the 1 ∶ 1 ∶ 1 paired of 106 groups,which include 106 cases of esophageal cancer,106 cases of esophageal precancerous lesions and 106 cases of normal control group.Results The levels of folic acid and VB 2 in serum of esophageal cancer group and esophageal precancerous lesions group were significantly lower than normal control group（P 0.05）,the level of folic acid in serum of esophageal cancer group was significantly lower than esophageal precancerous lesions group（P 0.05）,but the difference of the serum VB 2 of esophageal cancer group and esophageal precancerous lesions group was not statistically significant（P 0.05）.Conclusion the folic acid and vitamin B 2 deficiency has the relationship with the esophageal cancer occurrence and development.
出处
《卫生研究》
CAS
CSCD
北大核心
2013年第3期451-454,共4页
Journal of Hygiene Research
基金
达能膳食营养研究与宣教基金(DIC2011-05)
江苏省普通高校研究生科研创新计划(CXZZ-0179)
关键词
叶酸
VB2
食管癌
folic acid
vitamin B2
esophageal cancer
