摘要
目的:探讨多形性黄色瘤型星形细胞瘤的MRI表现及临床诊断价值。方法:回顾分析5例手术病理确诊为多形性黄色瘤型星形细胞瘤的MRI常规及功能成像表现。结果:4例表现为皮层-皮层下区域囊实性病变,1例表现为岛叶实性肿块,病变周围多为轻度水肿,增强后病变壁结节或实性肿块呈明显强化。DWI示病变呈等低信号,PWI示病变灌注升高(rCBV值2.96±0.64),MRS示病变区域Cho/NAA峰比值升高(2.03±1.08),Cho/Cr峰比值升高(1.77±0.69),NAA/Cr峰比值降低(0.94±0.38)。随访观察仅1例影像学表现具有恶性征象的患者术后复发,其余患者预后良好。结论:黄色瘤型星形细胞瘤MRI常规及功能成像表现具有一定特征性,且功能成像可在一定程度提供预后信息,正确认识其表现有助于提高诊断准确性及指导临床治疗。
Objective： To investigate the features and clinical application of MRI on pleomorphic xanthoastrocytoma.Methods： The conventional and functional MRI of five cases with pleomorphic xanthoastrocytoma confirmed by surgery and pathology were analyzed retrospectively.Results： Four cases showed solid and cystic lesions in the cortical-subcortical regions and one case showed insular cortex solid mass,most of which were surrounded by mild edema.Moreover,the mural nodule lesions or solid mass was obviously enhanced.DWI revealed low signal,PWI showed increased perfusion value（rCBV value of 2.96±0.64）,and MRS showed that the Cho/NAA peak ratio（2.03±1.08） and Cho/Cr peak ratio（1.77±0.69） were elevated,however,the NAA/Cr peak ratio was decreased（0.94±0.38）.The follow-up observation revealed that only one case with malignant signs in imaging findings had recurrence,and the prognosis of the other patients was good.Conclusions： Conventional and functional MRI have characteristics for pleomorphic xanthoastrocytoma diagnosis,and functional imaging may provide a prognostic information.To understand the features correctly may improve the diagnostic accuracy and guide the clinical treatment for pleomorphic xanthoastrocytoma.
出处
《中国临床医学影像杂志》
CAS
2013年第5期309-313,共5页
Journal of China Clinic Medical Imaging
基金
第三军医大学临床科研基金(2009XLC29)
重庆市自然科学基金重点项目(cstc2012jjB10028)
关键词
星形细胞瘤
磁共振成像
Astrocytoma
Magnetic resonance imaging
