摘要
经导管主动脉瓣置换术已经成为外科手术高危或存在手术禁忌证的重度主动脉瓣狭窄患者的一种新的治疗手段。心脏外科术后急性肾损伤与病死率增加显著相关,而需要肾脏替代治疗者预后更差。既往研究显示经导管主动脉瓣置换术术后急性肾损伤发生率约为1.1%～28%。近来,瓣膜学术研究协会在RIFLE分类的基础上提出了新的急性肾损伤定义标准。根据新标准,一些研究报道了经导管主动脉瓣置换术术后急性肾损伤发病率、预测因素以及临床预后并与之前的研究进行了比较。
Transcatheter aortic valve implantation （TAVI） has emerged as a new therapeutic option for non-operable or very high sur- gical high-risk patients with severe aortic stenosis. Acute kidney injury （AKI） after cardiac surgery is associated with increased mortality and necessity for renal replacement therapy even more so. Similarly AKI after TAVI is not infrequent affecting 1.1% -28% of patients in previ- ous series. Recently, a consensus report from the Valve Academic Research Consortium （VARC） suggested the new criteria for postproce- dural AKI based on modified RIFLE classification. Thus, according to the VARC criteria some studies have showed the probable incidence, predictors, and clinical outcome of AKI after TAVI and compare these outcomes with other previously used definitions.
出处
《心血管病学进展》
CAS
2013年第3期333-335,共3页
Advances in Cardiovascular Diseases
