摘要
目的:观察类风湿关节炎(RA)患者中医证候与血小板参数及病情活动指标的相关性。方法:从广西中医药大学第三附属医院收取RA患者128例,采用SPSS(11.0)建立数据库及统计研究其中医证候在年龄、性别、病程、发病年龄、类风湿因子(RF),血沉(ESR),C反应蛋白(CRP),血小板计数(PLT)、血小板压积(PCT)、血小板平均体积(MPV)、血小板分布宽度(PDW)等血小板参数方面的分布规律。结果:RA的不同证候在年龄、病程、病情活动情况、实验室指标上存在不同程度的差异。结论:桂中地区RA证候以湿热阻络最多见,且病程短,病情重,且多见于疾病活动期,ESR、CRP与其相关,MPV与湿热阻络相关,PLT、PCT与痰瘀互结相关,血小板参数与ESR、CRP及RF联合观察可以较好地反映出RA患者病情活动性和相关的中医证候,可作为指导临床辨证用药及判断中医药辨证的实验室指标。
Objective：To observe the variation of platelet parameter of rheumatoid arthritis and correlation of index of patients＇condition and clinical symptom. Method：128 cases＇RA activity come form the Third Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, then we used the SPSS 11.0 to analyze the index of patients＇condition of RA patients＂ platelet parameter （ RF, ESR, CRP, PLT, PCT, MPV, PDW）, and correlation of TCM symptoms such as age, sex, disease course,age of onset, frequency of petechia. Results ： There were significant difference in age, sex, disease course, age of onset, laboratory indexes. Conclusion： Rheumatoid arthritis with damp - heat blocking collaterals is one of the most common in Gui j~_ ong area, which has short course and severe acute abdomen in clinic. Patients with active disease have statistical higher levels of ESR, CRP. RA patients＇ MPV assumed to be positive correlation with symptoms of damp - heat blocking collaterals. RA patients＇PLT and PCT assumed to be positive correlation with symptoms of phlegm and blood stasis. Platelet parameter combined with ESR, CRP and RF is relevant with correlation of active index and TCM symptoms of rheumatoid arthritis in Guizhong area. This can be an index of laboratory.
出处
《中华中医药学刊》
CAS
2013年第6期1314-1316,共3页
Chinese Archives of Traditional Chinese Medicine
基金
广西自然科学基金面上项目(2010GXNSFA013258)
广西自治区中医药管理局科技专项课题资助项目(GZ-KZ09-58)
广西中医药大学自然科学研究课题资助项目(P2008051)
柳州市科技局科技攻关项目(2009021519)
