摘要
目的:探讨加味温胆汤联合黛力新治疗脑卒中后抑郁症(post stroke depression,PSD)的临床疗效。方法:60例PSD住院患者随机数字表单盲法分为治疗组和对照组,给予脑血管病常规治疗措施。对照组给予黛力新,治疗组在对照组基础上加用中药汤剂。用药前、用药2周及用药4周分别使用汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD)、汉密尔顿焦虑量表(Hamilton Anxiety Scale,HAMA)、日常生活活动能力量表(Activities of Daily Living Scale,ADL)(Barthel指数)判定。结果:两组患者治疗后HAMD、HAMA评分、ADL(Barthel指数)均较治疗前下降,与治疗前比较差异有统计学意义(P<0.05),治疗4周相比治疗2周有显著差异(P<0.05)。治疗组治疗后HAMD评分下降更为显著,与对照组相比差异有统计学意义(P<0.05)。治疗组治疗后ADL(Barthel指数)升高更为显著,与对照组相比差异有统计学意义(P<0.05)。结论:加味温胆汤联合黛力新治疗PSD较单用黛力新疗效显著。
Objective：To observe the clinical efficacy of the Jiaweiwendan Decoction combined with Deanxit for post stroke depression.Methods：60 cases of the PSD hospitalized patients were divided into the treatment group and the control group which were all given routine treatment of cerebrovascular diseases.The control group was given Deanxit while the treatment group were given Jiaweiwendan Decoction on the basis of Deanxit.The Hamilton Depression Scale（HAMD）,Hamilton Anxiety Scale（HAMA）,Activities of Daily Living Scale（ADL）（Barthel Index） were assessed before treatment,2 weeks and 4 weeks after treatment respectively.Results：After treatment,HAMD scones,HAMA scores and ADL（Barthel Index） of the two groups were reduced compared with before treatment,and the differences and statistical significance（P0.05）.4 weeks after treatment,HAMD soores,HAMA scores and ADL had significant differences comparing to 2 weeks after treatment（P0.05）.After tneatment,HAMD scores of the treatment group were lower than the control group,and the difference was statistically significant（P0.05）.And AOL（Barthel Index） were obviously higher than the control group after treatmtne,and the difference had statistical significance（P0.05）.Conclusion：Jiaweiwendan Decoction combined with Deanxit had significant difference compared to just using Deanxit for post stroke depression.
出处
《中医学报》
CAS
2013年第6期902-904,共3页
Acta Chinese Medicine
基金
河南省教育厅科学技术研究重点项目(编号:12A360004)
关键词
脑卒中后抑郁症
郁证
加味温胆汤
黛力新
poststroke depression
depression syndrome
jiaweiwendan decoction
deansit
