摘要
目的探讨羊膜腔内灌注治疗胎儿宫内发育受限(FGR)合并羊水过少的安全性和有效性。方法选取孕28～36周诊断FGR合并羊水过少、B超排除胎儿畸形的孕妇380例,随机分为治疗组和对照组。治疗组选用羊膜腔内灌注复方丹参注射液及氨基酸注射液治疗,对照组羊膜腔灌注林格液,治疗后均行静脉滴注复方丹参注射液加能量治疗1周。结果两组羊水指数比较,差异无统计学意义(P>0.05);两组股骨长度、双顶径的增长值和出生体重比较,治疗组均显著增加(P<0.05);两组剖宫产率比较,治疗组明显降低(P<0.05)。结论羊膜腔内灌注复方丹参注射液及氨基酸注射液治疗FGR合并羊水过少效果更好。
Objective To investigate the safety and effectiveness of amniotic infusion therapy for fetal growth restric- tion （FGR） combined with oligohydramnios. Methods Three hundred and eighty pregnant women, who were in gesta- tion of 28-36 weeks, diagnosed as fetal growth restriction combined with oligohydramnios, and excluded fetus malfor- mations by type B ultrasound, were selected and randomly assigned into treatment group and control group. The treat- ment group was treated by intra-amniotic infusion of compound salvia miltiorrhiza injection and amino acid injection, while the control group was treated by Ringer＇s solution. After treatment, both groups were also treated by intravenous infusion compound salvia miltiorrhiza injection and energy for one week. Results The gestational age and amniotic flu- id volume of two groups compared, the difference was not significant （P 〉 0.05）; the femur length, the growth value of biparietal diameter, and neonatal weight in treatment group were significantly increased （P 〈 0.05）; the rate of cesarean section of treatment group was significantly decreased compared with control group （P 〈 0.05）. Conclusion For fetal growth restriction combined with oligohydramnios, intra-amniotic infusion of compound salvia mihiorrhiza injection and amino acid injection has better therapeutic effect.
出处
《中国当代医药》
2013年第17期47-48,共2页
China Modern Medicine
关键词
羊膜腔内灌注
胎儿宫内发育受限
羊水过少
Intra-amniotic infusion
Fetus intrauterine growth restriction
Oligohydramnios
