摘要
目的 :筛选出经济有效的部队预防甲型病毒性肝炎的方案 ,为部队制定甲型病毒性肝炎防制策略提供依据。方法 :在决策理论模型的基础上 ,进行成本—效益分析 ;同时通过灵敏度分析法检验模型的稳定性。结果 :对于新兵、老兵、干部三组人群 ,其先筛选再接种方案的效益成本比 (BCR)均大于直接接种方案。三组人群之间比较 ,两种接种方案的BCR值均表现为干部高于新兵 ,新兵高于老兵 ,但两种方案均产生负效益。灵敏度分析结果显示 :各项费用参数值的减少对方案的BCR值有一定影响。随着疫苗保护期限延长 ,方案的BCR值显著增加 ,且接种方案有可能产生正效益。疫苗保护率的变化对BCR影响不明显。结论 :进一步降低接种方案的筛选费、疫苗费及提高疫苗保护作用的持久性 ,是部队开展大规模甲肝预防接种取得正效益的关键所在。
Objective:Selecting economic and effective programs for prevention of hepatitis A attack among military population,so as to lay a basis for making strategies of prevention and control of hepatitis A in our army.Methods:Cost-benefit analysis was performed based on decision model, and sensitivity analysis was made to examine stability of the model.Results:For recruits, veterans and officers,benefit-cost ratio (BCR) of all screening and vaccination (SV) programs was higher than that of direct vaccination (DV)programs.Among the three kinds of population, BCR of both SV programs and DV programs were higher for officers than those for recruits respectively, and recruits ,were higher than veteans ,,but both kinds of programs created negative benefit. Sensitivity analysis showed that changes of all kinds of cost,especially decrease of screening expense and vaccination expense,affected BCR of the programs.Meantime, with the prolongation of protection period for vaccine, BCR of the programs increased and could generate positive benefit.However,variation of the vaccine ,s protection rate did not influence BCR obviously.Conclusion: How to reduce the cost of a screening test and vaccination trial and increase duration of vaccine ,s protection remained critical to generae positive benefit if a wide-range vaccination was carried out among military people.
出处
《解放军预防医学杂志》
CAS
北大核心
2000年第4期251-253,共3页
Journal of Preventive Medicine of Chinese People's Liberation Army
基金
全军"九五"指令性课题! (No.96L0 49)
关键词
部队人群
甲肝疫苗
成本-效益分析
接种
military population, hepatitis A vaccine, cost-benefit analysis
