摘要
目的:探讨糖尿病对心肌血流储备分数(FFR)的影响,评价FFR指导糖尿病患者冠状动脉临界病变介入治疗的可靠性。方法:入选经定量冠状动脉造影示临界病变(狭窄40%～70%)且进行FFR测量的糖尿病患者21例,非糖尿病患者36例。依据管腔狭窄程度(40%～50%,51%～60%,61%～70%)进行分组,比较每组中糖尿病患者和非糖尿病患者FFR值的差异。结果:糖尿病患者临界病变共37处,非糖尿病患者临界病变共57处。冠状动脉狭窄程度相似时,糖尿病组和非糖尿病组的FFR值无统计学差异(P>0.05)。结论:糖尿病微血管病变对FFR值无显著影响,FFR指导糖尿病患者临界病变的介入治疗是可靠的。
Objective ： To investigate the effect of diabetes on fractional flow reserve （ FFR ） values, and assess the reliability of FFR measurement in guiding the interventional therapy in diabetic patients with coronary marginal lesions. Methods： Fifty-seven patients with coronary marginal lesions who undergone FFR measurement were enrolled in our study. The patients were divided according to the degree of the luminal narrowing（stenosis 40% - 50% ,51% - 60% ,61% - 70% ）. Then the FFR values of the patients with and without diabetes were compared in each category. Results：There were thirty-seven marginal lesions in diabetic groups, and fifty-seven lesions in non-diabetic patients. There was no significance between the FFR values of diabetic patients and non-diabetic patients who had similar degree of stenosis. Conclusion ： The disfunctional microvessels in diabetic patients does not have a significant impact on FFR values and FFR is reliable to guide the interventional therapy in diabetic patients with marginal stenosis.
出处
《河南医学研究》
CAS
2013年第3期324-326,共3页
Henan Medical Research
关键词
血流储备分数
临界病变
糖尿病
定量冠状动脉造影
fractional flow reserve
marginal lesion
diabetes mellitus
quantitative coronary angiography.
