摘要
[目的]探讨痰热清治疗慢性支气管炎(chronic bronchitis,CB)急性发作的疗效及对免疫球蛋白IgA、IgG和IgM的影响。[方法]将自2011年2月至2012年2月我院收治的60例CB急性发作患者随机分为对照组和观察组,每组30例。所有患者均给予基础治疗,对照组在基础治疗上给予庆大霉素、地塞米松、α糜蛋白酶雾化吸入,观察组则在基础治疗上给予痰热清注射液静脉滴注,观察两组患者的疗效、临床症状改善情况及免疫球蛋白IgA、IgG和IgM水平变化情况。[结果]观察组患者的总有效率为96.67%显著高于对照组的80%(χ2=4.04,P<0.05);观察组各临床症状的改善时间均明显短于对照组(P<0.05);观察组治疗后免疫球蛋白IgA、IgG和IgM的水平显著低于对照组(P<0.05)。[结论]采用痰热清治疗CB急性发作疗效显著,能有效缩短临床症状的缓解时间,改善免疫球蛋白IgA、IgG和IgM的水平,增强机体免疫功能,促进患者尽快康复。
[Objective] To explore the clinical efficacy of Tanreqing for treating acute exacerbation of chronic bronchitis and its impact on immunoglobulin levels of IgA,IgG and IgM.[Methods] 60 cases with acute exacerbation of chronic bronchitis admitted in our hospital from February 2010 to February 2012 were randomly divided into control group and observation group,and each group had 30 cases.All of the patients were given basic treatment;the control group was given gentamicin,dexamethasone and alpha chymotrypsin aerosol inhalation on the basis of the basic treatment,while the observation group was given Tanreqing intravenous injection;the efficacy,clinical symptoms improving situation and the changes of immunoglobulin levels of IgG and IgM were compared between the two groups.[Results] The total effective rate of the observation group was 96.67% significantly higher than 80% of the control group（χ2=4.04）;the clinical symptoms relieve time of the observation group was significantly shorter than the control group;after the treatment,the immunoglobulin levels of IgA,IgG,and IgM in the observation group were significantly lower than the control group.[Conclusion] Tanreqing has good clinical efficacy for treating acute exacerbation of chronic bronchitis;it can effectively shorten the duration of remission of clinical symptoms,im prove the immunoglobulin levels of IgA,IgG and IgM,enhance the immune function and promote the speedy recovery of the patients.
出处
《浙江中医药大学学报》
CAS
2013年第6期706-708,共3页
Journal of Zhejiang Chinese Medical University
关键词
CB
急性发作
痰热清
免疫球蛋白
chronic bronchitis
acute exacerbation
Tanreqing
immunoglobulin
